Up-and-coming anti-epileptic effect of aloesone in Aloe vera: Evidenced by integrating network pharmacological analysis, in vitro, and in vivo models

Y Wang, C Li, Z Xiong, N Chen, X Wang, J Xu… - Frontiers in …, 2022 - frontiersin.org
Background: Aloe vera is a medically valuable plant with anti-epileptic activity; however, its
mechanism of action remains unknown. In this study, network pharmacological, in vitro, and …

Potentials of miR-9-5p in promoting epileptic seizure and improving survival of glioma patients

S Wang, X He, N Bao, M Chen, X Ding, M Zhang… - Acta Epileptologica, 2022 - Springer
Background Epilepsy affects over 70 million people worldwide; however, the underlying
mechanisms remain unclear. MicroRNAs (miRNAs) have essential functions in epilepsy …

Ameliorating effect of ketogenic diet on acute status epilepticus: Insights into biochemical and histological changes in rat hippocampus

NI Shehata, MA Abdelsamad, HAA Amin… - Journal of Food …, 2022 - Wiley Online Library
This study aimed to evaluate the potential neuroprotective effects of ketogenic diet (KD)
against the neuronal disruptions induced by SE in lithium‐pilocarpine rat model of status …

Insertion of 643bp Retrotransposon Upstream of PPARγ CDS Is Associated with Backfat of Large White Pigs

J He, M Yu, C Chi, Z Du, Y Zheng, C Chen, AS Moawad… - Animals, 2023 - mdpi.com
Simple Summary Lipid metabolism has a substantial impact on the quality of meat in swine
farming. PPARγ has a close association with lipid metabolism and displays high expression …

Inherited L1 retrotransposon insertions associated with risk for schizophrenia and bipolar disorder

BC Reiner, GA Doyle, AE Weller… - Schizophrenia …, 2021 - academic.oup.com
Studies of the genetic heritability of schizophrenia and bipolar disorder examining single
nucleotide polymorphisms (SNPs) and copy number variations have failed to explain a large …

Genetic Investigations of Canine Idiopathic Epilepsy and Movement Disorders

CA Jenkins - 2023 - search.proquest.com
Dogs represent a fascinating species with dramatic variation in traits across hundreds of
breeds. Genetic bottlenecks, inbreeding, and selection for extreme phenotypes have led to …

Transcriptome analysis reveals higher levels of mobile element-associated abnormal gene transcripts in temporal lobe epilepsy patients

K Hu, P Liang - Frontiers in Genetics, 2021 - frontiersin.org
Mesial temporal lobe epilepsy (MTLE) is the most common form of epilepsy, and temporal
lobe epilepsy patients with hippocampal sclerosis (TLE-HS) show worse drug treatment …