[PDF][PDF] Wnt/Ca 2+ signaling pathway: a brief overview

A De - Acta Biochim. Biophys. Sin, 2011 - researchgate.net
The non-canonical Wnt/Ca2+ signaling cascade is less characterized than their canonical
counterpart, the Wnt/b-catenin pathway. The non-canonical Wnt signaling pathways are …

Parkinson's disease, aging and adult neurogenesis: Wnt/β‐catenin signalling as the key to unlock the mystery of endogenous brain repair

B Marchetti, C Tirolo, F L'Episcopo, S Caniglia… - Aging cell, 2020 - Wiley Online Library
A common hallmark of age‐dependent neurodegenerative diseases is an impairment of
adult neurogenesis. Wingless‐type mouse mammary tumor virus integration site (Wnt)/β …

Curcumin-Loaded Nanoparticles Potently Induce Adult Neurogenesis and Reverse Cognitive Deficits in Alzheimer's Disease Model via Canonical Wnt/β-Catenin …

SK Tiwari, S Agarwal, B Seth, A Yadav, S Nair… - ACS …, 2014 - ACS Publications
Neurogenesis, a process of generation of new neurons, is reported to be reduced in several
neurodegenerative disorders including Alzheimer's disease (AD). Induction of neurogenesis …

Blocking IL-1 signaling rescues cognition, attenuates tau pathology, and restores neuronal β-catenin pathway function in an Alzheimer's disease model

M Kitazawa, D Cheng, MR Tsukamoto… - The Journal of …, 2011 - journals.aai.org
Inflammation is a key pathological hallmark of Alzheimer's disease (AD), although its impact
on disease progression and neurodegeneration remains an area of active investigation …

Emerging roles of Wnts in the adult nervous system

NC Inestrosa, E Arenas - Nature Reviews Neuroscience, 2010 - nature.com
The roles of the Wnt signalling pathway in several developmental processes, including
synaptic differentiation, are well characterized. The expression of Wnt ligands and Wnt …

Mechanisms of melatonin in alleviating Alzheimer's disease

M Shukla, P Govitrapong, P Boontem… - Current …, 2017 - ingentaconnect.com
Alzheimer's disease (AD) is a chronic, progressive and prevalent neurodegenerative
disease characterized by the loss of higher cognitive functions and an associated loss of …

The beneficial role of photobiomodulation in neurodegenerative diseases

A Abijo, CY Lee, CY Huang, PC Ho, KJ Tsai - Biomedicines, 2023 - mdpi.com
Photobiomodulation (PBM), also known as Low-level Laser Therapy (LLLT), involves the
use of light from a laser or light-emitting diode (LED) in the treatment of various disorders …

Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1ΔE9 mouse model …

EM Toledo, NC Inestrosa - Molecular psychiatry, 2010 - nature.com
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by a progressive
deterioration of cognitive abilities, accumulation of the amyloid-β-peptide (Aβ) and synaptic …

Resveratrol inhibits beta-amyloid oligomeric cytotoxicity but does not prevent oligomer formation

Y Feng, X Wang, S Yang, Y Wang, X Zhang, X Du… - Neurotoxicology, 2009 - Elsevier
Beta-amyloid (Aβ) aggregation has been strongly associated with the neurodegenerative
pathology and a cascade of harmful event rated to Alzheimer's disease (AD). Inhibition of Aβ …

Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease

CC Liu, CW Tsai, F Deak, J Rogers, M Penuliar… - Neuron, 2014 - cell.com
Alzheimer's disease (AD) is an age-related neurological disorder characterized by synaptic
loss and dementia. The low-density lipoprotein receptor-related protein 6 (LRP6) is an …