Xenopus research: metamorphosed by genetics and genomics

RM Harland, RM Grainger - Trends in Genetics, 2011 - cell.com
Research using Xenopus takes advantage of large, abundant eggs and readily manipulated
embryos in addition to conserved cellular, developmental and genomic organization with …

The Genome of the Western Clawed Frog Xenopus tropicalis

U Hellsten, RM Harland, MJ Gilchrist, D Hendrix… - Science, 2010 - science.org
The western clawed frog Xenopus tropicalis is an important model for vertebrate
development that combines experimental advantages of the African clawed frog Xenopus …

Testis development and differentiation in amphibians

ÁS Roco, A Ruiz-García, M Bullejos - Genes, 2021 - mdpi.com
Sex is determined genetically in amphibians; however, little is known about the sex
chromosomes, testis-determining genes, and the genes involved in testis differentiation in …

Efficient targeted gene disruption in the soma and germ line of the frog Xenopus tropicalis using engineered zinc-finger nucleases

JJ Young, JM Cherone, Y Doyon… - Proceedings of the …, 2011 - National Acad Sciences
The frog Xenopus, an important research organism in cell and developmental biology,
currently lacks tools for targeted mutagenesis. Here, we address this problem by genome …

Evolution of the B7 family: co-evolution of B7H6 and NKp30, identification of a new B7 family member, B7H7, and of B7's historical relationship with the MHC

MF Flajnik, T Tlapakova, MF Criscitiello, V Krylov… - Immunogenetics, 2012 - Springer
The B7 family of genes is essential in the regulation of the adaptive immune system. Most B7
family members contain both variable (V)-and constant (C)-type domains of the …

Coexistence of Y, W, and Z sex chromosomes in Xenopus tropicalis

ÁS Roco, AW Olmstead, SJ Degitz… - Proceedings of the …, 2015 - National Acad Sciences
Homomorphic sex chromosomes and rapid turnover of sex-determining genes can
complicate establishing the sex chromosome system operating in a given species. This …

A chromosome-scale genome assembly and dense genetic map for Xenopus tropicalis

T Mitros, JB Lyons, AM Session, J Jenkins, S Shu… - Developmental …, 2019 - Elsevier
Abstract The Western clawed frog Xenopus tropicalis is a diploid model system for both frog
genetics and developmental biology, complementary to the paleotetraploid X. laevis. Here …

Divergent subgenome evolution in the allotetraploid frog Xenopus calcaratus

M Knytl, NR Fornaini, B Bergelová, V Gvoždík… - Gene, 2023 - Elsevier
Allopolyploid genomes are divided into compartments called subgenomes that are derived
from lower ploidy ancestors. In African clawed frogs of the subgenus Xenopus (genus …

Xenopus tropicalis as a Model Organism for Genetics and Genomics: Past, Present, and Future

RM Grainger - Xenopus Protocols: Post-Genomic Approaches, 2012 - Springer
Xenopus tropicalis was introduced as a model system for genetic, and then genomic
research, in the early 1990s, complementing work on the widely used model organism …

A new nomenclature of Xenopus laevis chromosomes based on the phylogenetic relationship to Silurana/Xenopus tropicalis

Y Matsuda, Y Uno, M Kondo, MJ Gilchrist… - … and genome research, 2015 - karger.com
Xenopus laevis (XLA) is an allotetraploid species which appears to have undergone whole-
genome duplication after the interspecific hybridization of 2 diploid species closely related to …