Chemotherapy is a life‐saving treatment for cancer patients, but also causes long‐term
cognitive impairment, or “chemobrain”, in survivors. However, several challenges, including …

MR elastography allows non-invasive quantification of the shear modulus of tissue, ie tissue
stiffness and viscosity, information that offers the potential to guide presurgical planning for …

In Europe, an estimated 4 million new cancer cases were diagnosed in 2020 (ECIS-
European Cancer Information System, 2023). Patients' chances of survival improved …

It has been established that cisplatin causes neuronal damage and cognitive impairment.
However, the mechanism is not sufficiently clear. Apelin-13 is an endogenous peptide with …

Effective cancer therapeutics for brain tumors must be able to cross the blood-brain barrier
(BBB) to reach the tumor in adequate quantities and overcome the resistance conferred by …

Oligodendrocytes are specialized cells that myelinate axons in the central nervous system.
Defects in oligodendrocyte function and failure to form or maintain myelin sheaths can cause …

There is growing evidence that chemotherapy may have a significant impact on the brains of
breast cancer patients, causing changes in cortical morphology. However, early …

Chemotherapy-induced neurodegeneration represents a significant challenge in cancer
survivorship, manifesting in cognitive impairments that severely affect patients' quality of life …

Background Many childhood cancer survivors develop neurocognitive impairment,
negatively affecting education and psychosocial functioning. Recommended comprehensive …

Background Although chemotherapy-induced leukoencephalopathy has been described in
case and cohort studies, literature remains inconclusive about its prevalence and …