SuperDendrix algorithm integrates genetic dependencies and genomic alterations across pathways and cancer types
Recent genome-wide CRISPR-Cas9 loss-of-function screens have identified genetic
dependencies across many cancer cell lines. Associations between these dependencies …
dependencies across many cancer cell lines. Associations between these dependencies …
The impact of the transcription factor MAF on physiology and malignant transformation in terminal B cell differentiation
M Werner - 2024 - refubium.fu-berlin.de
Multiple myeloma is a tumor of terminally differentiated B cells, ie, plasma cells (PCs), and
arises in the bone marrow (BM). Initial genetic events are acquired during the germinal …
arises in the bone marrow (BM). Initial genetic events are acquired during the germinal …