malERA: an updated research agenda for malaria elimination and eradication

RN Rabinovich, C Drakeley, AA Djimde, BF Hall… - PLoS …, 2017 - journals.plos.org
Achieving a malaria-free world presents exciting scientific challenges as well as
overwhelming health, equity, and economic benefits. WHO and countries are setting …

Novel molecular diagnostic tools for malaria elimination: a review of options from the point of view of high-throughput and applicability in resource limited settings

S Britton, Q Cheng, JS McCarthy - Malaria journal, 2016 - Springer
As malaria transmission continues to decrease, an increasing number of countries will enter
pre-elimination and elimination. To interrupt transmission, changes in control strategies are …

The temporal dynamics and infectiousness of subpatent Plasmodium falciparum infections in relation to parasite density

HC Slater, A Ross, I Felger, NE Hofmann… - Nature …, 2019 - nature.com
Malaria infections occurring below the limit of detection of standard diagnostics are common
in all endemic settings. However, key questions remain surrounding their contribution to …

Comparison of diagnostics for the detection of asymptomatic Plasmodium falciparum infections to inform control and elimination strategies

L Wu, LL van den Hoogen, H Slater, PGT Walker… - Nature, 2015 - nature.com
The global burden of malaria has been substantially reduced over the past two decades.
Future efforts to reduce malaria further will require moving beyond the treatment of clinical …

False-negative malaria rapid diagnostic test results and their impact on community-based malaria surveys in sub-Saharan Africa

OJ Watson, KM Sumner, M Janko, V Goel, P Winskill… - BMJ global …, 2019 - gh.bmj.com
Surveillance and diagnosis of Plasmodium falciparum malaria relies predominantly on rapid
diagnostic tests (RDT). However, false-negative (FN) RDT results are known to occur for a …

Performance of rapid diagnostic test, blood-film microscopy and PCR for the diagnosis of malaria infection among febrile children from Korogwe District, Tanzania

C Mahende, B Ngasala, J Lusingu, TS Yong, P Lushino… - Malaria journal, 2016 - Springer
Background Rapid diagnostic tests (RDT) and light microscopy are still recommended for
diagnosis to guide the clinical management of malaria despite difficult challenges in rural …

Simulation models predict that school-age children are responsible for most human-to-mosquito Plasmodium falciparum transmission in southern Malawi

JE Coalson, LM Cohee, AG Buchwald, A Nyambalo… - Malaria journal, 2018 - Springer
Background Malaria persists in some high-transmission areas despite extensive control
efforts. Progress toward elimination may require effective targeting of specific human …

Submicroscopic carriage of Plasmodium falciparum and Plasmodium vivax in a low endemic area in Ethiopia where no parasitaemia was detected by microscopy or …

FG Tadesse, H Pett, A Baidjoe, K Lanke, L Grignard… - Malaria journal, 2015 - Springer
Background Motivated by the success in malaria control that was documented over the last
decade Ethiopia is aiming at malaria elimination by 2020 in selected districts. It is currently …

malERA: An updated research agenda for diagnostics, drugs, vaccines, and vector control in malaria elimination and eradication

malERA Refresh Consultative Panel on Tools for … - PLoS …, 2017 - journals.plos.org
Since the turn of the century, a remarkable expansion has been achieved in the range and
effectiveness of products and strategies available to prevent, treat, and control malaria …

Malaria rapid diagnostic tests reliably detect asymptomatic Plasmodium falciparum infections in school-aged children that are infectious to mosquitoes

LM Hofer, PA Kweyamba, RM Sayi, MS Chabo… - Parasites & …, 2023 - Springer
Abstract Background Asymptomatic malaria infections (Plasmodium falciparum) are
common in school-aged children and represent a disease transmission reservoir as they are …