Synthesis of coumarin-thioether conjugates as potential anti-tubercular agents: Their molecular docking and X-ray crystal studies

M Akki, DS Reddy, KS Katagi, A Kumar… - Journal of Molecular …, 2022 - Elsevier
In this work, we report a series of 4-(2, 6-dimethylphenyl) thio) methyl)-2H-chromen-2-one
conjugates as promising leads to treat tuberculosis. Spectroscopic and other analytical …

Discovery of benzochromene derivatives first example with dual cytotoxic activity against the resistant cancer cell MCF-7/ADR and inhibitory effect of the P …

LM Al-Harbi, EA Al-Harbi, RM Okasha… - Journal of enzyme …, 2023 - Taylor & Francis
A series of 1 H-benzo [f] chromene moieties (4a–z) were synthesised under Ultrasonic
irradiation and confirmed with spectral analyses. Derivative 4i solely possessed an X-ray …

Design, synthesis and in vitro α-glucosidase inhibition of novel coumarin-pyridines as potent antidiabetic agents

M Adib, F Peytam, M Rahmanian-Jazi… - New Journal of …, 2018 - pubs.rsc.org
In this work, we report an efficient, one-pot and three-component synthesis of novel
coumarin fused pyridine derivatives 4a–p. Heating the mixture of 4-hydroxycoumarins and …

Benzocoumarins: isolation, synthesis, and biological activities

HN Lv, PF Tu, Y Jiang - Mini Reviews in Medicinal Chemistry, 2014 - ingentaconnect.com
Benzocoumarins are coumarins with a phenyl group bonded to 3, 4-, 5, 6-, 6, 7-, or 7, 8-
positions. Over the past years, significant efforts have been made not only to isolate the …

[DABCO-C18] Br: A novel basic surfactant for the synthesis of dihydropyrano [3, 2-c] chromenes and 2-aminobenzochromenes under ambient conditions

A Rajmane, R Bandal, S Shirke, U More, S Patil… - Journal of Molecular …, 2023 - Elsevier
We successfully produced a new surfactant called [DABCO-C 18] Br, which is a
monoquaternized octadecyl-1, 4-diazabicyclo [2.2. 2] octane bromide. The yield was good …

[PDF][PDF] Iraqi Journal of Pharmacy

M Jebir, RN Ismael, O Qutachi - Iraqi Journal of Pharmacy, 2023 - researchgate.net
Background: Coumarins and their derivatives excel in chemical diversity, coupled with a
wide variety of biological potentials, and tend to be beneficial to the health of the human …

Design of New Benzo[h]chromene Derivatives: Antitumor Activities and Structure-Activity Relationships of the 2,3-Positions and Fused Rings at the 2,3-Positions

RM Okasha, FF Alblewi, TH Afifi, A Naqvi, AM Fouda… - Molecules, 2017 - mdpi.com
A series of novel 4 H-benzo [h] chromenes 4, 6–11, 13, 14; 7 H-benzo [h] chromeno [2, 3-d]
pyrimidines 15–18, 20, and 14 H-benzo [h] chromeno [3, 2-e][1, 2, 4] triazolo [1, 5-c] …

Photocatalytic dehydrogenated etherification of 2-aryl benzylic alcohols

Z Liang, C Liu, J Fan, M Wang, X Yan, M Huang… - Green …, 2022 - pubs.rsc.org
Here we describe an efficient and practical method for the conversion of 2-aryl benzylic
alcohols into the corresponding chromenes through visible-light-induced photoredox …

Design and synthesis of new series of coumarin–aminopyran derivatives possessing potential anti-depressant-like activity

KV Sashidhara, RK Modukuri, S Singh, KB Rao… - Bioorganic & Medicinal …, 2015 - Elsevier
A new series of coumarin based aminopyran derivatives were designed, synthesized and
evaluated for their preclinical antidepressant effect on Swiss albino mice. Among the series …

Design, synthesis, in vivo, and in silico evaluation of new coumarin-1, 2, 4-oxadiazole hybrids as anticonvulsant agents

M Mohammadi-Khanaposhtani, N Ahangar… - Bioorganic …, 2019 - Elsevier
A novel series of coumarin-1, 2, 4-oxadiazole hybrids were designed, synthesized, and
evaluated as anticonvulsant agents. The title compounds were easily synthesized from …