Eph receptor tyrosine kinases and the corresponding ephrin ligands play a pivotal role in the
glioma development and progression. Aberrant protein expression levels of the Eph …

Background: Eph receptors play important functions in developmental processes and
diseases and among them EphA2 is well known for its controversial role in cancer. Drug …

Understanding the host anti-fungal immunity induced by beta-glucan has been one of the
most challenging conundrums in the field of biomedical research. During the last couple of …

The sterile α motif (SAM) domain of the ephrin receptor tyrosine kinase, EphA2, undergoes
tyrosine phosphorylation, but the effect of phosphorylation on the structure and interactions …

The receptor tyrosine kinase EPHA2 is overexpressed in several cancers (breast, head and
neck, non‐small‐cell lung cancer). Small‐molecule‐based inhibition of the EPHA2 kinase …

The receptor tyrosine kinase RET is essential in a variety of cellular processes. RET gain-of-
function is strongly associated with several cancers, notably multiple endocrine neoplasia …

Oral defense should be able to sense the burden of, and distinguish between fungal
commensals and pathogens, so that an adequate inflammatory response can be set up …

Fibroblast growth factor receptors (FGFRs) are a family of receptor tyrosine kinases
containing three domains: an extracellular receptor domain, a single transmembrane helix …

Receptor tyrosine kinases (RTKs) are an important class of transmembrane receptors that
mediate some of the most crucial biochemical pathways essential to the growth …

Colorectal cancer (CRC) is a global health problem. It is the second leading cause of cancer
related death worldwide and in Australia. Around 25% of CRC will experience recurrences …