Ruthenium complexes in the fight against pathogenic microorganisms. An extensive review

AC Munteanu, V Uivarosi - Pharmaceutics, 2021 - mdpi.com
The widespread use of antibiotics has resulted in the emergence of drug-resistant
populations of microorganisms. Clearly, one can see the need to develop new, more …

Quinine conjugates and quinine analogues as potential antimalarial agents

RA Jones, SS Panda, CD Hall - European journal of medicinal chemistry, 2015 - Elsevier
Malaria is a tropical disease, prevalent in Southeast Asia and Africa, resulting in over half a
million deaths annually; efforts to develop new antimalarial agents are therefore particularly …

The elements of life and medicines

P Chellan, PJ Sadler - Philosophical Transactions of the …, 2015 - royalsocietypublishing.org
Which elements are essential for human life? Here we make an element-by-element journey
through the periodic table and attempt to assess whether elements are essential or not, and …

Privileged S-Triazines: Structure and Pharmacological Applications

DR Shah, RP Modh, KH Chikhalia - Future medicinal chemistry, 2014 - Taylor & Francis
This review summarizes recent reports on s-triazine and its respective analogs from the
medicinal chemistry angle. Due to its high reactivity and binding characteristic towards …

Synthesis and antimalarial activity of metal complexes of cross-bridged tetraazamacrocyclic ligands

TJ Hubin, PNA Amoyaw, KD Roewe… - Bioorganic & medicinal …, 2014 - Elsevier
Using transition metals such as manganese (II), iron (II), cobalt (II), nickel (II), copper (II), and
zinc (II), several new metal complexes of cross-bridged tetraazamacrocyclic chelators …

Transition Metal Complexes as Antimalarial Agents: A Review

A Mandal, R Kushwaha, AA Mandal, S Bajpai… - …, 2023 - Wiley Online Library
In antimalarial drug development research, overcoming drug resistance has been a major
challenge for researchers. Nowadays, several drugs like chloroquine, mefloquine …

Exploring Ruthenium‐Based Organometallic Inhibitors against Plasmodium falciparum Calcium Dependent Kinase 2 (PfCDPK2): A Combined Ensemble Docking, QM …

D Patel, M Athar, PC Jha - ChemistrySelect, 2021 - Wiley Online Library
Recent advances in the metal‐organic framework (MOF) have accelerated the discovery of
novel metal‐based anticancer, antibacterial and antimalarial compounds. This is …

Synthesis and antiproliferative activity of benzimidazole-based, trinuclear neutral cyclometallated and cationic, N^ N-chelated ruthenium (ii) complexes

A Welsh, L Rylands, VB Arion, S Prince… - Dalton Transactions, 2020 - pubs.rsc.org
A series of 2-phenyl and 2-pyridyl tris-benzimidazole ligands was reacted with the [Ru (p-
cymene) Cl2] 2 dimer to yield the corresponding neutral cyclometallated and cationic …

3-acetyl-coumarin-substituted thiosemicarbazones and their ruthenium, rhodium and iridium metal complexes: An investigation of the antibacterial, antioxidant and …

CGL Nongpiur, C Soh, DF Diengdoh, AK Verma… - Journal of …, 2023 - Elsevier
A series of ruthenium, iridium and rhodium half-sandwich complexes containing 3-acetyl
chromen-2-one-4 (N)-substituted thiosemicarbazone derivatives have been prepared for …

Investigating the antiplasmodial activity of substituted cyclopentadienyl rhodium and iridium complexes of 2-(2-pyridyl) benzimidazole

L Jordaan, MT Ndlovu, S Mkhize, S Ngubane… - Journal of …, 2022 - Elsevier
Six cationic half-sandwich Ir (III) and Rh (III) complexes (C1-C6) were synthesised by
reaction of 2-(2-pyridyl) benzimidazole with the appropriate chloro-bridged dimers. All …