Breaking the convention: sialoglycan variants, coreceptors, and alternative receptors for influenza A virus entry
U Karakus, MO Pohl, S Stertz - Journal of virology, 2020 - Am Soc Microbiol
The influenza A virus (IAV) envelope protein hemagglutinin binds α2, 6-or α2, 3-linked sialic
acid as a host cell receptor. Bat IAV subtypes H17N10 and H18N11 form an exception to this …
acid as a host cell receptor. Bat IAV subtypes H17N10 and H18N11 form an exception to this …
Bat influenza viruses: current status and perspective
Bats are natural reservoirs for many viruses, including several that are zoonotic. Two
unusual H17N10 and H18N11 influenza viruses have been found in New World bats …
unusual H17N10 and H18N11 influenza viruses have been found in New World bats …
Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus
H Kleine-Weber, S Schroeder, N Krüger… - Emerging microbes & …, 2020 - Taylor & Francis
Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) causes a severe
respiratory disease in humans. The MERS-CoV spike (S) glycoprotein mediates viral entry …
respiratory disease in humans. The MERS-CoV spike (S) glycoprotein mediates viral entry …
TMPRSS2 is the major activating protease of influenza A virus in primary human airway cells and influenza B virus in human type II pneumocytes
H Limburg, A Harbig, D Bestle, DA Stein… - Journal of …, 2019 - Am Soc Microbiol
Cleavage of influenza virus hemagglutinin (HA) by host cell proteases is essential for virus
infectivity and spread. We previously demonstrated in vitro that the transmembrane protease …
infectivity and spread. We previously demonstrated in vitro that the transmembrane protease …
Mutations in the spike protein of Middle East respiratory syndrome coronavirus transmitted in Korea increase resistance to antibody-mediated neutralization
H Kleine-Weber, MT Elzayat, L Wang… - Journal of …, 2019 - Am Soc Microbiol
Middle East respiratory syndrome coronavirus (MERS-CoV) poses a threat to public health.
The virus is endemic in the Middle East but can be transmitted to other countries by travel …
The virus is endemic in the Middle East but can be transmitted to other countries by travel …
Assessment of risk conferred by coding and regulatory variations of TMPRSS2 and CD26 in susceptibility to SARS-CoV-2 infection in human
At present, more than 200 countries and territories are directly affected by the coronavirus
disease-19 (COVID-19) pandemic. Incidence and case fatality rate are significantly higher …
disease-19 (COVID-19) pandemic. Incidence and case fatality rate are significantly higher …
Entry of the bat influenza H17N10 virus into mammalian cells is enabled by the MHC class II HLA-DR receptor
Haemagglutinin and neuraminidase surface glycoproteins of the bat influenza H17N10 virus
neither bind to nor cleave sialic acid receptors, indicating that this virus employs cell entry …
neither bind to nor cleave sialic acid receptors, indicating that this virus employs cell entry …
Tools to study pathogen-host interactions in bats
Bats are natural reservoirs for a variety of emerging viruses that cause significant disease in
humans and domestic animals yet rarely cause clinical disease in bats. The co-evolutionary …
humans and domestic animals yet rarely cause clinical disease in bats. The co-evolutionary …
Synthetically derived bat influenza A-like viruses reveal a cell type-but not species-specific tropism
ÉA Moreira, S Locher, L Kolesnikova… - Proceedings of the …, 2016 - National Acad Sciences
Two novel influenza A-like viral genome sequences have recently been identified in Central
and South American fruit bats and provisionally designated “HL17NL10” and “HL18NL11.” …
and South American fruit bats and provisionally designated “HL17NL10” and “HL18NL11.” …
Membrane-anchored serine proteases: host cell factors in proteolytic activation of viral glycoproteins
E Böttcher-Friebertshäuser - Activation of Viruses by Host Proteases, 2018 - Springer
Over one third of all known proteolytic enzymes are serine proteases. Among these, the
trypsin-like serine proteases comprise one of the best characterized subfamilies due to their …
trypsin-like serine proteases comprise one of the best characterized subfamilies due to their …