The multiple faces of RAGE–opportunities for therapeutic intervention in aging and chronic disease
R Ramasamy, A Shekhtman… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: This review focuses on the multi-ligand receptor of the immunoglobulin
superfamily–receptor for advanced glycation endproducts (RAGE). The accumulation of the …
superfamily–receptor for advanced glycation endproducts (RAGE). The accumulation of the …
Small molecule inhibition of ligand-stimulated RAGE-DIAPH1 signal transduction
MB Manigrasso, J Pan, V Rai, J Zhang, S Reverdatto… - Scientific reports, 2016 - nature.com
The receptor for advanced glycation endproducts (RAGE) binds diverse ligands linked to
chronic inflammation and disease. NMR spectroscopy and x-ray crystallization studies of the …
chronic inflammation and disease. NMR spectroscopy and x-ray crystallization studies of the …
[HTML][HTML] Chronic sustained inflammation links to left ventricular hypertrophy and aortic valve sclerosis: a new link between S100/RAGE and FGF23
L Yan, MAH Bowman - Inflammation and cell signaling, 2014 - ncbi.nlm.nih.gov
Background Cardiovascular disease including left ventricular hypertrophy, diastolic
dysfunction and ectopic valvular calcification are common in patients with chronic kidney …
dysfunction and ectopic valvular calcification are common in patients with chronic kidney …
Improved cardiac-specific delivery of RAGE siRNA within small extracellular vesicles engineered to express intense cardiac targeting peptide attenuates myocarditis
H Kim, D Mun, JY Kang, SH Lee, N Yun… - … Therapy-Nucleic Acids, 2021 - cell.com
Small extracellular vesicles (sEVs) are nanometer-sized membranous vesicles secreted by
cells, with important roles in physiological and pathological processes. Recent research has …
cells, with important roles in physiological and pathological processes. Recent research has …
RAGE plays a role in LPS-induced NF-κB activation and endothelial hyperpermeability
L Wang, J Wu, X Guo, X Huang, Q Huang - Sensors, 2017 - mdpi.com
Endothelial functional dysregulation and barrier disruption contribute to the initiation and
development of sepsis. The receptor for advanced glycation end products (RAGE) has been …
development of sepsis. The receptor for advanced glycation end products (RAGE) has been …
The receptor for advanced glycation endproducts (RAGE) contributes to severe inflammatory liver injury in mice
T Weinhage, T Wirth, P Schütz, P Becker… - Frontiers in …, 2020 - frontiersin.org
Background: The receptor for advanced glycation end products (RAGE) is a multiligand
receptor involved in a number of processes and disorders. While it is known that RAGE …
receptor involved in a number of processes and disorders. While it is known that RAGE …
Helicobacter pylori Activates HMGB1 Expression and Recruits RAGE into Lipid Rafts to Promote Inflammation in Gastric Epithelial Cells
HJ Lin, FY Hsu, WW Chen, CH Lee, YJ Lin… - Frontiers in …, 2016 - frontiersin.org
Helicobacter pylori infection is associated with several gastrointestinal disorders in the
human population worldwide. High-mobility group box 1 (HMGB1), a ubiquitous nuclear …
human population worldwide. High-mobility group box 1 (HMGB1), a ubiquitous nuclear …
The clinical significance of circulating soluble RAGE in patients with severe sepsis
H Matsumoto, N Matsumoto, H Ogura… - Journal of Trauma …, 2015 - journals.lww.com
BACKGROUND The receptor for advanced glycation end products (RAGE) is a pattern-
recognition receptor involved in the pathogenesis of inflammatory diseases. However, the …
recognition receptor involved in the pathogenesis of inflammatory diseases. However, the …
Coalescence of RAGE in lipid rafts in response to cytolethal distending toxin-induced inflammation
HJ Lin, ZP Jiang, HR Lo, CL Feng, CJ Chen… - Frontiers in …, 2019 - frontiersin.org
The receptor for advanced glycation end products (RAGE) interacts with various molecules
in the cell membrane to induce an inflammatory response. The cytolethal distending toxin …
in the cell membrane to induce an inflammatory response. The cytolethal distending toxin …
Receptor for Advanced Glycation End Products (RAGE) Serves a Protective Role during Klebsiella pneumoniae - Induced Pneumonia
A Achouiti, AF de Vos, C van 't Veer, S Florquin… - PLoS …, 2016 - journals.plos.org
Klebsiella species is the second most commonly isolated gram-negative organism in sepsis
and a frequent causative pathogen in pneumonia. The receptor for advanced glycation end …
and a frequent causative pathogen in pneumonia. The receptor for advanced glycation end …