The diagnosis and treatment of rectal cancer have evolved dramatically over the past
several decades. At the same time, its incidence has increased in younger populations. This …

This selection from the NCCN Guidelines for Rectal Cancer focuses on management of
malignant polyps and resectable nonmetastatic rectal cancer because important updates …

PURPOSE Prospective data on the efficacy of a watch-and-wait strategy to achieve organ
preservation in patients with locally advanced rectal cancer treated with total neoadjuvant …

Neoadjuvant chemoradiotherapy (NACRT) or chemotherapy (NACT) followed by radical
resection and then adjuvant therapy is considered the optimal treatment model for locally …

Background & Aims Patients with early-onset colorectal cancer (eoCRC) are managed
according to guidelines that are not age-specific. A multidisciplinary international group …

Chemoradiotherapy is a widely used treatment for patients with malignancies such as
hepatocellular carcinoma (HCC). However, it remains challenging to realize safe and …

Neoadjuvant therapy is standard of care for locally advanced rectal cancer (LARC).
Advancements in multimodality therapy options and sequencing of radiation therapy (RT) …

In the past 40 years, the treatment of locally advanced rectal cancer has evolved with the
addition of radiotherapy or chemoradiotherapy and providing (neo) adjuvant systemic …

Simple Summary The management of rectal cancer has become increasingly more complex.
Over the recent year, the use of chemotherapy and radiation before surgical intervention has …

Abstract The Society of Abdominal Radiology's Colorectal and Anal Cancer Disease-
Focused Panel (DFP) first published a rectal cancer lexicon paper in 2019. Since that time …