Neurotrophic factors in Huntington's disease

J Alberch, E Pérez-Navarro, JM Canals - Progress in brain research, 2004 - Elsevier
Huntington's disease is a neurodegenerative disorder characterized by the selective loss of
striatal neurons and, to a lesser extent, cortical neurons. The neurodegenerative process is …

Neurotrophic support and oxidative stress: converging effects in the normal and diseased nervous system

J Gardiner, D Barton, R Overall, J Marc - The Neuroscientist, 2009 - journals.sagepub.com
Oxidative stress and loss of neurotrophic support play major roles in the development of
various diseases of the central and peripheral nervous systems. In disorders of the central …

FGF-2 promotes neurogenesis and neuroprotection and prolongs survival in a transgenic mouse model of Huntington's disease

K Jin, M LaFevre-Bernt, Y Sun… - Proceedings of the …, 2005 - National Acad Sciences
There is no satisfactory treatment for Huntington's disease (HD), a hereditary
neurodegenerative disorder that produces chorea, dementia, and death. One potential …

Neurotrophic factors and neurodegenerative diseases: a delivery issue

B Ruozi, D Belletti, L Bondioli, A De Vita… - Int Rev …, 2012 - books.google.com
Neurotrophic factors (NTFs) represent one of the most stimulating challenge in
neurodegenerative diseases, due to their potential in neurorestoring and neuroprotection …

NGF and nitrosative stress in patients with Huntington's disease

I Tasset, F Sánchez-López, E Agüera… - Journal of the …, 2012 - Elsevier
INTRODUCTION: Huntington's disease (HD) is a neurodegenerative genetic disorder
caused by expansion of polyglutamine repeats in the huntingtin gene and characterised by …

Experimental and clinical strategies for treating spinocerebellar ataxia type 3

Z Wang - Neuroscience, 2018 - Elsevier
Abstract Spinocerebellar ataxia type 3 (SCA3), or Machado–Joseph disease (MJD), is an
autosomal dominant neurodegenerative disorder caused by the expansion of a …

Phytocannabinoids and cannabimimetic drugs: recent patents in central nervous system disorders

R Ranieri, D Marasco, M Bifulco… - Recent Patents on …, 2015 - ingentaconnect.com
Background: Starting from the chemical structure of phytocannabinoids, isolated from
Cannabis sativa plant, research groups designed numerous cannabimimetic drugs. These …

Cannabinoids for use in the treatment of neurodegenerative diseases or disorders

T Iuvone, V Di Marzo, G Guy, S Wright… - US Patent 10,258,580, 2019 - Google Patents
The present invention relates to cannabinoids for use in the prevention or treatment of
neurodegenerative diseases or disorders. Preferably the cannabinoids are …

Changes in nNOS and NADPH diaphorase in frog retina and tectum after axotomy and FGF-2 application

I Soto, T López-Roca, JM Blagburn, RE Blanco - Brain research, 2006 - Elsevier
We have shown previously that application of fibroblast growth factor-2 (FGF-2) to the cut
optic nerve of the frog, Rana pipiens, augments the survival of retinal ganglion cells (RGCs) …

[PDF][PDF] Comprendre la contribution de la circulation sanguine dans l'expression et l'atténuation d'aspects pathologiques associés à la maladie de Huntington

M Rieux - 2020 - dam-oclc.bac-lac.gc.ca
Résumé La maladie de Huntington (MH) est une maladie neurodégénérative génétique qui
se caractérise par des déficits moteurs ainsi que des troubles cognitifs et psychiatriques …