Toxoplasma gondii is an obligate intracellular pathogen within the phylum Apicomplexa.
This protozoan parasite is one of the most widespread, with a broad host range including …

The Apicomplexa are a phylum of diverse obligate intracellular parasites including
Plasmodium spp., the cause of malaria; Toxoplasma gondii and Cryptosporidium parvum …

As with other organisms with a completed genome sequence, opportunities for performing
large-scale studies, such as expression and localization, on Toxoplasma gondii are now …

Many protozoans of the phylum Apicomplexa are invasive parasites that exhibit a substrate-
dependent gliding motility. Plasmodium (malaria) sporozoites, the stage of the parasite that …

Polymorphic rhoptry-secreted kinases (ROPs) are essential virulence factors of Toxoplasma
gondii. In particular, the pseudokinase ROP5 is the major determinant of acute virulence in …

Apicomplexan parasites, including Toxoplasma gondii, apically attach to their host cells
before invasion. Recent studies have implicated the contents of micronemes, which are …

Toxoplasma gondii is an obligate intracellular parasite that actively invades a wide variety of
vertebrate cells, although the basis of its pervasive cell invasion is not completely …

Host-cell invasion by apicomplexan parasites involves the successive exocytosis of three
different secretory organelles; namely micronemes, rhoptries and dense granules. The …

Plasmodium and Toxoplasma belong to a group of unicellular parasites which actively
penetrate their respective mammalian host cells. During the process of invasion, they initiate …

Host cell invasion by apicomplexan parasites requires coordinated interactions between cell
surface adhesins and the parasite cytoskeleton. We have identified a complex of parasite …