Translational opportunities and challenges of invasive electrodes for neural interfaces

K Shen, O Chen, JL Edmunds, DK Piech… - Nature Biomedical …, 2023 - nature.com
Invasive brain–machine interfaces can restore motor, sensory and cognitive functions.
However, their clinical adoption has been hindered by the surgical risk of implantation and …

Implantable intracortical microelectrodes: reviewing the present with a focus on the future

Y Wang, X Yang, X Zhang, Y Wang… - Microsystems & …, 2023 - nature.com
Implantable intracortical microelectrodes can record a neuron's rapidly changing action
potentials (spikes). In vivo neural activity recording methods often have either high temporal …

Tissue damage thresholds during therapeutic electrical stimulation

SF Cogan, KA Ludwig, CG Welle… - Journal of neural …, 2016 - iopscience.iop.org
Objective. Recent initiatives in bioelectronic modulation of the nervous system by the NIH
(SPARC), DARPA (ElectRx, SUBNETS) and the GlaxoSmithKline Bioelectronic Medicines …

Restoring sensorimotor function through intracortical interfaces: progress and looming challenges

SJ Bensmaia, LE Miller - Nature Reviews Neuroscience, 2014 - nature.com
The loss of a limb or paralysis resulting from spinal cord injury has devastating
consequences on quality of life. One approach to restoring lost sensory and motor abilities in …

[HTML][HTML] Restoration of vision in blind individuals using bionic devices: a review with a focus on cortical visual prostheses

PM Lewis, HM Ackland, AJ Lowery, JV Rosenfeld - Brain research, 2015 - Elsevier
The field of neurobionics offers hope to patients with sensory and motor impairment.
Blindness is a common cause of major sensory loss, with an estimated 39 million people …

Abiotic-biotic characterization of Pt/Ir microelectrode arrays in chronic implants

A Prasad, QS Xue, R Dieme, V Sankar… - Frontiers in …, 2014 - frontiersin.org
Pt/Ir electrodes have been extensively used in neurophysiology research in recent years as
they provide a more inert recording surface as compared to tungsten or stainless steel …

Clinical applications of penetrating neural interfaces and Utah Electrode Array technologies

RA Normann, E Fernandez - Journal of neural engineering, 2016 - iopscience.iop.org
This paper briefly describes some of the recent progress in the development of penetrating
microelectrode arrays and highlights the use of two of these devices, Utah electrode arrays …

Neural stimulation and recording performance in human sensorimotor cortex over 1500 days

CL Hughes, SN Flesher, JM Weiss… - Journal of Neural …, 2021 - iopscience.iop.org
Objective. Intracortical microstimulation (ICMS) in somatosensory cortex can restore
sensation to people with spinal cord injury. However, the recording quality from implanted …

Honeycomb-shaped electro-neural interface enables cellular-scale pixels in subretinal prosthesis

T Flores, T Huang, M Bhuckory, E Ho, Z Chen… - Scientific reports, 2019 - nature.com
High-resolution visual prostheses require small, densely packed pixels, but limited
penetration depth of the electric field formed by a planar electrode array constrains such …

Electronic approaches to restoration of sight

GA Goetz, DV Palanker - Reports on Progress in Physics, 2016 - iopscience.iop.org
Retinal prostheses are a promising means for restoring sight to patients blinded by the
gradual atrophy of photoreceptors due to retinal degeneration. They are designed to …