With new data about different aspects of schizophrenia being continually generated, it
becomes necessary to periodically revisit exactly what we know. Along with a need to review …

Various environmental exposures have been associated with psychosis spectrum disorder.
However, the role of gender in this association has received little attention. Therefore, we …

Although schizophrenia is currently conceptualized as being characterized as a syndrome
that includes a collection of signs and symptoms, there is strong evidence of heterogeneous …

Treatment-resistant symptoms occur in about a third of patients with schizophrenia and are
associated with a substantial reduction in their quality of life. The development of new …

Background Social determinants of health (SDoHs) are nonmedical factors that significantly
impact health and longevity. We found no published reviews on the biology of SDoHs in …

It has been reported that cumulative measures of risk factors for psychosis might help to
predict its development. However, it remains unknown as to whether these measures are …

Psychotic disorders are highly debilitating with poor prognoses and courses of chronic
illness. In recent decades, conceptual models have shaped understanding, informed …

In this study we use aggregated weighted scores of environmental effects to study
environmental influences on well-being and happiness. To this end, we split a sample of …

Background Genetic and environmental factors contribute to the pathogenesis of
schizophrenia (SZ) and bipolar disorder (BD). Among genetic risk groups stratified by …

Background Evidence suggests that environmental factors not only increase psychosis
liability but also influence the prognosis and outcomes of psychotic disorders. We …