A systematic review of the valproic-acid-induced rodent model of autism
D Chaliha, M Albrecht, M Vaccarezza… - Developmental …, 2020 - karger.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterised by
repetitive behaviours, cognitive rigidity/inflexibility, and social-affective impairment …
repetitive behaviours, cognitive rigidity/inflexibility, and social-affective impairment …
[HTML][HTML] Three decades of valproate: a current model for studying autism Spectrum disorder
D Zarate-Lopez, AL Torres-Chávez… - Current …, 2023 - ncbi.nlm.nih.gov
Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with increased
prevalence and incidence in recent decades. Its etiology remains largely unclear, but it …
prevalence and incidence in recent decades. Its etiology remains largely unclear, but it …
Sex differences in spatial learning and memory and hippocampal long-term potentiation at perforant pathway-dentate gyrus (PP-DG) synapses in Wistar rats
Background Recent studies show that gender may have a significant impact on brain
functions. However, the reports of sex effects on spatial ability and synaptic plasticity in …
functions. However, the reports of sex effects on spatial ability and synaptic plasticity in …
Prangos ferulacea (L.) ameliorates behavioral alterations, hippocampal oxidative stress markers, and apoptotic deficits in a rat model of autism induced by valproic …
M Saadat, AA Taherian, MR Aldaghi… - Brain and …, 2023 - Wiley Online Library
Background Prenatal exposure to valproic acid (VPA) may enhance the risk of autism
spectrum disorder (ASD) in children. This study investigated the effect of Prangos ferulacea …
spectrum disorder (ASD) in children. This study investigated the effect of Prangos ferulacea …
Probiotics and prebiotics alleviate behavioral deficits, inflammatory response, and gut dysbiosis in prenatal VPA-induced rodent model of autism
Autism spectrum disorders are neuropsychiatric conditions characterized by social
interaction and communication disorders and repetitive stereotypical behaviors. These …
interaction and communication disorders and repetitive stereotypical behaviors. These …
Chronic inhibition of astrocytic aquaporin-4 induces autistic-like behavior in control rat offspring similar to maternal exposure to valproic acid
Social communication and interaction deficits, memory impairment, and anxiety-like
behavior are characterized in many people identified with autism spectrum disorder (ASD) …
behavior are characterized in many people identified with autism spectrum disorder (ASD) …
Alterations of the hippocampal networks in valproic acid-induced rat autism model
Autism Spectrum Disorder (ASD) is one of the most frequently diagnosed
neurodevelopmental disorders, characterized among others by impairments in social …
neurodevelopmental disorders, characterized among others by impairments in social …
Sex differences in spatial learning and memory in valproic acid rat model of autism: possible beneficial role of exercise interventions
In the current study, we first tried to determine sex differences in spatial learning and
memory in the valproic acid (VPA) rat model of autism. Second, the effects of interval training …
memory in the valproic acid (VPA) rat model of autism. Second, the effects of interval training …
Sex and genotype modulate the dendritic effects of developmental exposure to a human-relevant polychlorinated biphenyls mixture in the juvenile mouse
KP Keil Stietz, S Sethi, CR Klocke… - Frontiers in …, 2021 - frontiersin.org
While many neurodevelopmental disorders (NDDs) are thought to result from interactions
between environmental and genetic risk factors, the identification of specific gene …
between environmental and genetic risk factors, the identification of specific gene …
An anticonvulsive drug, valproic acid (valproate), has effects on the biosynthesis of fatty acids and polyketides in microorganisms
P Poolchanuan, P Unagul, S Thongnest, S Wiyakrutta… - Scientific reports, 2020 - nature.com
Valproic acid or valproate (VPA) is an anticonvulsive drug used for treatments of epilepsy,
bipolar disorder, and migraine headaches. VPA is also an epigenetic modulator, inhibiting …
bipolar disorder, and migraine headaches. VPA is also an epigenetic modulator, inhibiting …