High mortality and morbidity rates and variable clinical behavior are hallmarks of
glioblastoma (GBM), the most common and aggressive primary malignant brain tumor …

MicroRNAs (miRNAs) are small noncoding RNAs that could regulate gene expressions
transcriptionally or post-transcriptionally through binding to 3'untranslated region (3'UTR) of …

Backgrounds: Emerging evidences has demonstrated that dysregulation of long non-coding
RNAs (lncRNAs) is critically involved in esophageal squamous cell carcinoma (ESCC) …

Background Emerging evidence indicates that dysregulation of microRNAs (miRNAs)
contributes to cervical cancer (CC) tumorigenesis and development. Previous work showed …

Rationale: Atherosclerosis is a chronic inflammatory and epigenetic disease that is
influenced by different patterns of blood flow. However, the epigenetic mechanism whereby …

Glioblastoma multiforme (GBM) is the most common primary malignant tumors originating in
the brain parenchyma. At present, GBM patients have a poor prognosis despite the …

Endothelial cell inflammatory activation and dysfunction are key events in the
pathophysiology of atherosclerosis, and are associated with an elevated risk of …

Polycomb proteins are critical chromatin modifiers that regulate stem cell differentiation via
transcriptional repression. In skeletal muscle progenitors Enhancer of zeste homologue 2 …

The transcription factor MYC is overexpressed in many human cancers and has a significant
causal role in tumor incidence and progression. In contrast, Myc+/− heterozygous mice …

In the past decade, significant advances in molecular research have provided a deeper
understanding of the intricate regulatory mechanisms involved in carcinogenesis …