[HTML][HTML] Adjustable viscoelasticity allows for efficient collective cell migration

EH Barriga, R Mayor - Seminars in cell & developmental biology, 2019 - Elsevier
Cell migration is essential for a wide range of biological processes such as embryo
morphogenesis, wound healing, regeneration, and also in pathological conditions, such as …

Viscoelasticity, like forces, plays a role in mechanotransduction

CT Mierke - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Viscoelasticity and its alteration in time and space has turned out to act as a key element in
fundamental biological processes in living systems, such as morphogenesis and motility …

The basic concept of viscoelasticity

I Pajic-Lijakovic - Viscoelasticity and collective cell migration, 2021 - Elsevier
Viscoelasticity of multicellular system represents a product of energy storage and dissipation
during cell rearrangement under various stress or strain conditions and should be …

The rearrangement of co-cultured cellular model systems via collective cell migration

I Pajic-Lijakovic, R Eftimie, M Milivojevic… - Seminars in Cell & …, 2023 - Elsevier
Cancer invasion through the surrounding epithelium and extracellular matrix (ECM) is the
one of the main characteristics of cancer progression. While significant effort has been made …

Long-time viscoelasticity of multicellular surfaces caused by collective cell migration–multi-scale modeling considerations

I Pajic-Lijakovic, M Milivojevic - Seminars in Cell & Developmental Biology, 2019 - Elsevier
Long-time viscoelasticity of multicellular surfaces caused by collective cell migration
depends on:(1) the volume fraction and configuration of migrating cells and the rate of its …

Mechanical waves caused by collective cell migration: generation

I Pajic-Lijakovic, M Milivojevic - European Biophysics Journal, 2022 - Springer
Long-timescale viscoelasticity caused by collective cell migration (CCM) significantly
influences cell rearrangement and induces generation of mechanical waves. The …

Viscoelasticity and cell jamming state transition

I Pajic-Lijakovic, M Milivojevic - The European Physical Journal Plus, 2021 - Springer
Although collective cell migration (CCM) is a highly coordinated migratory mode,
perturbations in the form of jamming state transitions and vice versa often occur even in 2D …

Mechanical oscillations in 2D collective cell migration: the elastic turbulence

I Pajic-Lijakovic, M Milivojevic - Frontiers in Physics, 2020 - frontiersin.org
Various types of mechanical waves, such as propagative waves and standing waves, are
observed during 2D collective cell migration. Propagative waves are generated during …

The role of viscoelasticity in long time cell rearrangement

I Pajic-Lijakovic, M Milivojevic - Progress in Biophysics and Molecular …, 2022 - Elsevier
Cell rearrangement caused by collective cell migration (CCM) during free expansion of
epithelial monolayers has become a landmark in our current understanding of fundamental …

Nonlinear elastic and inelastic properties of cells

W Jung, J Li, O Chaudhuri… - Journal of …, 2020 - asmedigitalcollection.asme.org
Mechanical forces play an important role in various physiological processes, such as
morphogenesis, cytokinesis, and migration. Thus, in order to illuminate mechanisms …