Siglec-mediated regulation of immune cell function in disease

MS Macauley, PR Crocker, JC Paulson - Nature Reviews Immunology, 2014 - nature.com
All mammalian cells display a diverse array of glycan structures that differ from those that are
found on microbial pathogens. Siglecs are a family of sialic acid-binding immunoglobulin …

Host modulation therapy with anti‐inflammatory agents

PM Preshaw - Periodontology 2000, 2018 - Wiley Online Library
Host modulation therapy refers to a treatment concept in which drug therapies are used as
an adjunct to conventional periodontal treatment to ameliorate destructive aspects of the …

Denosumab and osteonecrosis of the jaw. A systematic analysis of events reported in clinical trials

A Boquete‐Castro, G Gómez‐Moreno… - Clinical oral implants …, 2016 - Wiley Online Library
Objectives The aims of this meta‐analysis were (i) to perform a systematic review of the
relation between treatment with denosumab and the incidence of osteonecrosis of the jaw …

Denosumab: a potential new and innovative treatment option for aneurysmal bone cysts

T Lange, C Stehling, B Fröhlich, M Klingenhöfer… - European Spine …, 2013 - Springer
Abstract Introduction Aneurysmal bone cysts (ABCs) are expansive and destructive lesions
positive for osteoclast markers, resembling benign giant cell tumors (GCTs). Treatment …

WNT signaling in bone development and homeostasis

Z Zhong, NJ Ethen, BO Williams - Wiley Interdisciplinary …, 2014 - Wiley Online Library
The balance between bone formation and bone resorption controls postnatal bone
homeostasis. Research over the last decade has provided a vast amount of evidence that …

Denosumab and giant cell tumour of bone—a review and future management considerations

SF Xu, B Adams, XC Yu, M Xu - Current Oncology, 2013 - pmc.ncbi.nlm.nih.gov
Giant cell tumour of bone (gctb) is one type of giant-cell-rich bone lesion characterized by
the presence of numerous multinucleated osteoclast-type giant cells. Giant cells are known …

The Belgian Bone Club 2020 guidelines for the management of osteoporosis in postmenopausal women

D Sanchez-Rodriguez, P Bergmann, JJ Body… - Maturitas, 2020 - Elsevier
Purpose To provide updated evidence-based guidelines for the management of
osteoporosis in postmenopausal women in Belgium. Methods The Belgian Bone Club (BBC) …

Denosumab in patients with aneurysmal bone cysts: a case series with preliminary results

E Palmerini, P Ruggieri, A Angelini, S Boriani… - Tumori …, 2018 - journals.sagepub.com
Purpose: Aneurysmal bone cyst (ABC) is a rare skeletal tumor usually treated with
surgery/embolization. We hypothesized that owing to similarities with giant cell tumor of …

Targeting receptor-activator of nuclear kappaB ligand in aneurysmal bone cysts: verification of target and therapeutic response

DW Pelle, JW Ringler, JD Peacock… - Translational …, 2014 - Elsevier
Aneurysmal bone cyst (ABC) is a benign tumor of bone presenting as a cystic, expansile
lesion in both the axial and appendicular skeleton. Axial lesions demand special …

Recomendaciones de la Sociedad Española de Reumatología sobre osteoporosis

AN Hernández, PD del Campo Fontecha, MPA Acín… - Reumatología clínica, 2019 - Elsevier
Objective To update the recommendations on osteoporosis (OP) of the Spanish Society of
Rheumatology (SER) based on the best possible evidence. Methods A panel of nine expert …