Gas chromatography-mass spectrometry analysis of synthetic opioids belonging to the fentanyl class: a review

CA Valdez - Critical Reviews in Analytical Chemistry, 2022 - Taylor & Francis
The rising number of deaths caused by fentanyl overdosing in the US due to the
overwhelming illicit use of this synthetic opioid has started a global campaign to develop …

[图书][B] Forensic chemistry

S Bell - 2022 - taylorfrancis.com
Forensic Chemistry, Third Edition, the new edition of this ground-breaking book, continues to
serve as the leading forensic chemistry text on the market. Fully updated, this edition …

Classification of fentanyl analogues through principal component analysis (PCA) and hierarchical clustering of GC–MS data

N Gilbert, RE Mewis, OB Sutcliffe - Forensic Chemistry, 2020 - Elsevier
The emergence of a wide variety of fentanyl analogues has become a problem for the
identification of seized drug samples. While chemical databases are largely reactive to the …

Forensic seized drug analysis: Current challenges and emerging analytical solutions

M Joshi, E Sisco - Wiley Interdisciplinary Reviews: Forensic …, 2023 - Wiley Online Library
Over the past decade, new challenges in seized drug analysis have pushed the limits of
existing instrumentation and workflows. These challenges include increasing caseloads …

NIST Mass Spectrometry Data Center standard reference libraries and software tools: Application to seized drug analysis

WE Wallace, AS Moorthy - Journal of forensic sciences, 2023 - Wiley Online Library
The standard reference libraries and associated custom software provided by the National
Institute of Standards and Technology's Mass Spectrometry Data Center (NIST MSDC) are …

Spectral trends in GC-EI-MS data obtained from the SWGDRUG mass spectral library and literature: A resource for the identification of unknown compounds

W Feeney, AS Moorthy, E Sisco - Forensic Chemistry, 2022 - Elsevier
Rapid identification of new or emerging psychoactive substances remains a critical
challenge in forensic drug chemistry laboratories. Current analytical protocols are well …

Machine learning model for detecting fentanyl analogs from mass spectra

P Koshute, N Hagan, NJ Jameson - Forensic Chemistry, 2022 - Elsevier
In recent years, fentanyl and its analogs have been increasingly abused, leading to tragic
outcomes. One way to tackle this problem is to rapidly detect fentanyl analog compounds …

Comprehensive Data Evaluation Methods Used in Developing the SWGDRUG Mass Spectral Reference Library for Seized Drug Identification

W Ji, WE Wallace - Analytical Chemistry, 2024 - ACS Publications
The mass spectral library of the Scientific Working Group for the Analysis of Seized Drugs
(SWGDRUG) is the most comprehensive free reference database of its kind in the world. It …

Expert algorithm for substance identification using mass spectrometry: application to the identification of cocaine on different instruments using binary classification …

SA Mehnert, JT Davidson, A Adeoye… - Journal of the …, 2023 - ACS Publications
This is the second of two manuscripts describing how general linear modeling (GLM) of a
selection of the most abundant normalized fragment ion abundances of replicate mass …

Screening unknown novel psychoactive substances using GC–MS based machine learning

SL Wong, LT Ng, J Tan, J Pan - Forensic Chemistry, 2023 - Elsevier
In recent years, there is a large increase in structural diversity of novel psychoactive
substances (NPS), exacerbating drug abuse issues as these variants evade classical …