Protein–protein interactions (PPIs) are one of the next major classes of therapeutic targets,
although they are too intricate to tackle with standard approaches. This is due, in part, to the …

In order to minimize expensive drug failures, is essential to determine potential activity,
toxicity and ADME problems as early as possible. In view of the large libraries of compounds …

The Support vector regression (SVR) was used to investigate quantitative structure–activity
relationships (QSAR) of 75 phenolic compounds with Trolox-equivalent antioxidant capacity …

Les flavonoïdes sont des produits largement distribués dans le règne végétal et sont
couramment consommés quotidiennement sous forme de fruits, légumes et boissons telles …

Variable selection is a procedure used to select the most important features to obtain as
much information as possible from a reduced amount of features. The selection stage is …

There is evidence that hyperglycemia results in the generation of reactive oxygen species,
leading to oxidative stress in various tissues, including vascular system. An important link …

Protein-protein interactions (PPIs) may represent one of the next major classes of
therapeutic targets. So far, only a minute fraction of the estimated 650,000 PPIs that …

Chlorophyll and anthocyanin contents provide a valuable indicator of the status of a plant's
physiology, but to be more widely utilized it needs to be assessed easily and non …

Enterovirus 71 (EV71) can cause severe disease and even lead to death in children, and an
effective antiviral drug is currently unavailable. The anti-EV71 effect of chrysin (5, 7 …

MATERIALS AND METHODS Chemicals First grade solvents were used for extraction,
fractionation and column chromatography. Kiesel gel 60 (70—230 mesh, Art, 7734 Merck) …