Zika virus (ZIKV)—a member of the Flaviviridae family—is an important human pathogen. Its
genome encodes a polyprotein that can be further processed into structural and non …

Zika virus (ZIKV) has emerged as a significant public health threat, reaching pandemic
levels in 2016. Human infection with ZIKV can manifest as either asymptomatic or as an …

In this paper we investigate 10 different HIV protease inhibitors (HPIs) as possible
repurposed-drugs candidates against SARS-CoV-2. To this end, we execute molecular …

The NS2B/NS3 protease is highly conserved among various proteases of the Zika virus,
making it an important therapeutic target for developing broad-spectrum antiviral drugs. The …

Zika virus (ZIKV), which is associated with severe diseases in humans, has spread rapidly
and globally since its emergence. ZIKV and dengue virus (DENV) are closely related, and …

Structural genomics involves the advent of three-dimensional structures of the genome
encoded proteins through various techniques available. Numerous structural genomics …

Viral proteases are an important target for drug development, since they can modulate vital
pathways in viral replication, maturation, assembly and cell entry. With the (re) appearance …

The World Health Organization has designated Zika virus (ZIKV) as a dangerous, mosquito‐
borne flaviviral pathogen that was recently found to be responsible for a dramatically …

Zika virus is a member of the Flaviviridae family and genus Flavivirus, which has a
phylogenetic relationship with spondweni virus. It spreads to humans through a mosquito …

The Zika virus (ZIKV) is believed to cause birth defects, and no anti-ZIKV drugs have been
approved by medical organizations to date. Starting from antimicrobial lead compounds with …