Evidence shows that environmental compounds can interfere with the endocrine systems of
wildlife and humans. The main sink of such substances, called endocrine disruptors (EDs) …

The expression of the thyroid hormone (TH) receptor genes alpha (TR alpha) and beta (TR
beta) in Xenopus laevis begins after the embryo hatches. The TR alpha mRNA increases …

Recent work on a diverse array of echinoderm species has demonstrated, as is true in
amphibians, that thyroid hormone (TH) accelerates development to metamorphosis …

Evolutionary transitions in larval nutritional mode have occurred on numerous occasions
independently in many marine invertebrate phyla. Although the evolutionary transition from …

The axolotl, Ambystoma mexicanum, has been an important model system in both
developmental and evolutionary biology for over 100 years. The axolotl is a recently derived …

The Mexican axolotl (Ambystoma mexicanum) presents an excellent model to investigate
mechanisms of brain development that are conserved among vertebrates. In particular …

Background Thyroid hormones (TH) induce gene expression programs that orchestrate
amphibian metamorphosis. In contrast to anurans, many salamanders do not undergo …

A single gene is thought to control paedomorphosis in the axolotl, Ambystoma mexicanum.
However, recent studies of related ambystomatids that show a facultative life-history …

Mechanistic interpretations of the diversity in urodele cranial ontogenies have focused
largely on the primary distinctions of metamorphic versus paedomorphic forms and obligate …

Abstract Background The Mexican axolotl (Ambystoma mexicanum) is considered a hopeful
monster because it exhibits an adaptive and derived mode of development-paedomorphosis …