Kinetochores are large protein assemblies that connect chromosomes to microtubules of the
mitotic and meiotic spindles in order to distribute the replicated genome from a mother cell to …

Kinetochores are molecular machines that power chromosome segregation during the
mitotic and meiotic cell divisions of all eukaryotes. Aristotle explains how we think we have …

Fungal pathogens pose a global threat to human health, with Candida albicans among the
leading killers. Systematic analysis of essential genes provides a powerful strategy to …

Kinetochores, multisubunit protein assemblies, connect chromosomes to spindle
microtubules to promote chromosome segregation. The 10-subunit KMN assembly …

Kinetochores are proteinaceous scaffolds implicated in the formation of load-bearing
attachments of chromosomes to microtubules during mitosis. Kinetochores contain distinct …

Chromosomes are carriers of genetic material and their accurate transfer from a mother cell
to its two daughters during cell division is of paramount importance for life. Kinetochores are …

The propagation of all organisms depends on the accurate and orderly segregation of
chromosomes in mitosis and meiosis. Budding yeast has long served as an outstanding …

Centromeres direct the assembly of kinetochores, microtubule-attachment sites that allow
chromosome segregation on the mitotic spindle. Fundamental differences in size and …

Kinetochores connect centromeric nucleosomes with mitotic-spindle microtubules through
conserved, cross-interacting protein subassemblies. In budding yeast, the heterotetrameric …

The spindle assembly checkpoint controls cell cycle progression during mitosis,
synchronizing it with the attachment of chromosomes to spindle microtubules. After the …