Campylobacter vaccination reduces diarrheal disease and infant growth stunting among rhesus macaques

SM Hendrickson, A Thomas, HP Raué… - Nature …, 2023 - nature.com
Campylobacter-associated enteric disease is estimated to be responsible for more than 160
million cases of gastroenteritis each year and is linked to growth stunting of infants living …

Recent advances and challenges in developing vaccines for Campylobacter jejuni: a comprehensive review

S Poudel, X Zeng, J Lin, WH Cheng… - World's Poultry …, 2024 - Taylor & Francis
Campylobacter jejuni remains a leading cause of food-borne gastroenteritis worldwide, with
contaminated poultry meat being a major transmission vector to humans. Effective control of …

Development of a next-generation chikungunya virus vaccine based on the HydroVax platform

DK Slifka, HP Raué, WC Weber, TF Andoh… - PLoS …, 2022 - journals.plos.org
Chikungunya virus (CHIKV) is an emerging/re-emerging mosquito-borne pathogen
responsible for explosive epidemics of febrile illness characterized by debilitating …

[HTML][HTML] Growth faltering regardless of chronic diarrhea is associated with mucosal immune dysfunction and microbial dysbiosis in the gut lumen

NS Rhoades, SM Hendrickson, K Prongay, A Haertel… - Mucosal …, 2021 - Elsevier
Despite the impact of childhood diarrhea on morbidity and mortality, our understanding of its
sequelae has been significantly hampered by the lack of studies that examine samples …

Diversity of Campylobacter spp. circulating in a rhesus macaque (Macaca mulatta) breeding colony using culture and molecular methods

RL Bacon, CL Hodo, J Wu, S Welch, C Nickodem… - mSphere, 2024 - journals.asm.org
Campylobacter jejuni and Campylobacter coli represent the leading causes of bacterial
gastroenteritis in humans, and infections can produce post-infectious irritable bowel …

Reduced infant rhesus macaque growth rates due to environmental enteric dysfunction and association with histopathology in the large intestine

SM Hendrickson, A Thomas, K Prongay… - Nature …, 2022 - nature.com
Environmental enteric dysfunction is associated with malnutrition as well as infant growth
stunting and has been classically defined by villous blunting, decreased crypt-to-villus ratio …

Trivalent outer membrane vesicles-based combination vaccine candidate induces protective immunity against Campylobacter and invasive non-typhoidal Salmonella …

S Banerjee, P Halder, S Das, S Maiti, JH Withey… - Medical Microbiology …, 2024 - Springer
Campylobacter and invasive non-typhoidal Salmonella (iNTS) are among the most common
causative agents of gastroenteritis worldwide. As of now, no single combination licensed …

Infant diarrheal disease in rhesus macaques impedes microbiome maturation and is linked to uncultured Campylobacter species

NS Rhoades, IR Cinco, SM Hendrickson… - Communications …, 2024 - nature.com
Diarrheal diseases remain one of the leading causes of death for children under 5 globally,
disproportionately impacting those living in low-and middle-income countries (LMIC) …

Characterisation of N-linked protein glycosylation in the bacterial pathogen Campylobacter hepaticus

JB McDonald, NE Scott, GJ Underwood… - Scientific Reports, 2023 - nature.com
Campylobacter hepaticus is an important pathogen which causes Spotty Liver Disease
(SLD) in layer chickens. SLD results in an increase in mortality and a significant decrease in …

Identification of novel small molecule inhibitors of twin arginine translocation (Tat) pathway and their effect on the control of Campylobacter jejuni in chickens

L Deblais, M Drozd, A Kumar, J Antwi, J Fuchs… - Frontiers in …, 2024 - frontiersin.org
Introduction Control of Campylobacter from farm to fork is challenging due to the frequent
emergence of antimicrobial-resistant isolates. Furthermore, poultry production systems are …