Foundation models for generalist medical artificial intelligence

M Moor, O Banerjee, ZSH Abad, HM Krumholz… - Nature, 2023 - nature.com
The exceptionally rapid development of highly flexible, reusable artificial intelligence (AI)
models is likely to usher in newfound capabilities in medicine. We propose a new paradigm …

Algorithmic fairness in artificial intelligence for medicine and healthcare

RJ Chen, JJ Wang, DFK Williamson, TY Chen… - Nature biomedical …, 2023 - nature.com
In healthcare, the development and deployment of insufficiently fair systems of artificial
intelligence (AI) can undermine the delivery of equitable care. Assessments of AI models …

Data drift in medical machine learning: implications and potential remedies

B Sahiner, W Chen, RK Samala… - The British Journal of …, 2023 - academic.oup.com
Data drift refers to differences between the data used in training a machine learning (ML)
model and that applied to the model in real-world operation. Medical ML systems can be …

Machine learning in precision diabetes care and cardiovascular risk prediction

EK Oikonomou, R Khera - Cardiovascular Diabetology, 2023 - Springer
Artificial intelligence and machine learning are driving a paradigm shift in medicine,
promising data-driven, personalized solutions for managing diabetes and the excess …

Targeted validation: validating clinical prediction models in their intended population and setting

M Sperrin, RD Riley, GS Collins, GP Martin - Diagnostic and prognostic …, 2022 - Springer
Clinical prediction models must be appropriately validated before they can be used. While
validation studies are sometimes carefully designed to match an intended population/setting …

Algorithm fairness in ai for medicine and healthcare

RJ Chen, TY Chen, J Lipkova, JJ Wang… - arXiv preprint arXiv …, 2021 - arxiv.org
In the current development and deployment of many artificial intelligence (AI) systems in
healthcare, algorithm fairness is a challenging problem in delivering equitable care. Recent …

EHR foundation models improve robustness in the presence of temporal distribution shift

LL Guo, E Steinberg, SL Fleming, J Posada… - Scientific Reports, 2023 - nature.com
Temporal distribution shift negatively impacts the performance of clinical prediction models
over time. Pretraining foundation models using self-supervised learning on electronic health …

[HTML][HTML] Why did AI get this one wrong?—Tree-based explanations of machine learning model predictions

E Parimbelli, TM Buonocore, G Nicora… - Artificial Intelligence in …, 2023 - Elsevier
Increasingly complex learning methods such as boosting, bagging and deep learning have
made ML models more accurate, but harder to interpret and explain, culminating in black …

Evaluation of domain generalization and adaptation on improving model robustness to temporal dataset shift in clinical medicine

LL Guo, SR Pfohl, J Fries, AEW Johnson, J Posada… - Scientific reports, 2022 - nature.com
Temporal dataset shift associated with changes in healthcare over time is a barrier to
deploying machine learning-based clinical decision support systems. Algorithms that learn …

[HTML][HTML] Empirical evaluation of performance degradation of machine learning-based predictive models–A case study in healthcare information systems

Z Young, R Steele - International Journal of Information Management Data …, 2022 - Elsevier
While there have been a very large number of academic studies of proposed machine
learning-based health predictive models, it is widely recognized that machine learning …