Malignant pleural effusion and its current management: a review

K Skok, G Hladnik, A Grm, A Crnjac - Medicina, 2019 - mdpi.com
Malignant pleural effusion (MPE) is an exudative effusion with malignant cells. MPE is a
common symptom and accompanying manifestation of metastatic disease. It affects up to …

An update on predictive biomarkers for treatment selection in non-small cell lung cancer

T Ahmadzada, S Kao, G Reid, M Boyer… - Journal of Clinical …, 2018 - mdpi.com
It is now widely established that management of lung cancer is much more complex and
cannot be centered on the binary classification of small-cell versus non-small cell lung …

Molecular pathology of lung cancer

JJ Saller, TA Boyle - Cold Spring Harbor …, 2022 - perspectivesinmedicine.cshlp.org
This overview of the molecular pathology of lung cancer includes a review of the most
salient molecular alterations of the genome, transcriptome, and the epigenome. The insights …

Extracellular vesicles as biomarkers in malignant pleural mesothelioma: A review

T Ahmadzada, S Kao, G Reid, S Clarke… - Critical Reviews in …, 2020 - Elsevier
Extracellular vesicles (EV) are secreted by all cells, including cancer cells, as a mode of
intercellular transport and communication. The main types of EV known to date include …

Genomics and functional genomics of malignant pleural mesothelioma

E Cakiroglu, S Senturk - International Journal of Molecular Sciences, 2020 - mdpi.com
Malignant pleural mesothelioma (MPM) is a rare, aggressive cancer of the mesothelial cells
lining the pleural surface of the chest wall and lung. The etiology of MPM is strongly …

Epigenetic investigation into circulating microRNA 197-3p in sera from patients affected by malignant pleural mesothelioma and workers ex-exposed to asbestos

G Di Mauro, F Frontini, E Torreggiani, MR Iaquinta… - Scientific Reports, 2023 - nature.com
The epigenetic role of microRNAs is established at both physiological and pathological
levels. Dysregulated miRNAs and their targets appear to be a promising approach for …

Are circulating microRNAs suitable for the early detection of malignant mesothelioma? Results from a nested case–control study

DG Weber, A Brik, S Casjens, K Burek, M Lehnert… - BMC Research …, 2019 - Springer
Objective Malignant mesothelioma is an aggressive cancer of the serous membranes. For
the detection of the tumor at early stages non-or minimally-invasive biomarkers are needed …

New vistas in malignant mesothelioma: MicroRNA architecture and NRF2/MAPK signal transduction

M Gandhi, S Nair - Life Sciences, 2020 - Elsevier
Malignant mesothelioma (MM) is a cancer of the mesothelial lining of the pleura,
peritoneum, pericardium and testes. The most common form is asbestos-linked MM that is …

High BIN1 expression has a favorable prognosis in malignant pleural mesothelioma and is associated with tumor infiltrating lymphocytes

T Ahmadzada, K Lee, C Clarke, WA Cooper, A Linton… - Lung Cancer, 2019 - Elsevier
Objectives A number of key immune regulators show prognostic value in malignant pleural
mesothelioma (MPM), but the association between Bridging integrator 1 (BIN1), indoleamine …

Small and Large Extracellular Vesicles Derived from Pleural Mesothelioma Cell Lines Offer Biomarker Potential

T Ahmadzada, A Vijayan, F Vafaee, A Azimi, G Reid… - Cancers, 2023 - mdpi.com
Simple Summary Pleural mesothelioma, a fatal thoracic cancer with one of the poorest
survival rates of any cancer, is in urgent clinical need for biomarkers to aid early diagnosis …