Biological roles of adenine methylation in RNA

K Boulias, EL Greer - Nature Reviews Genetics, 2023 - nature.com
Abstract N 6-Methyladenosine (m6A) is one of the most abundant modifications of the
epitranscriptome and is found in cellular RNAs across all kingdoms of life. Advances in …

Vitamin C—sources, physiological role, kinetics, deficiency, use, toxicity, and determination

M Doseděl, E Jirkovský, K Macáková, LK Krčmová… - Nutrients, 2021 - mdpi.com
Vitamin C (L-ascorbic acid) has been known as an antioxidant for most people. However, its
physiological role is much larger and encompasses very different processes ranging from …

[HTML][HTML] 13 reasons why the brain is susceptible to oxidative stress

JN Cobley, ML Fiorello, DM Bailey - Redox biology, 2018 - Elsevier
The human brain consumes 20% of the total basal oxygen (O 2) budget to support ATP
intensive neuronal activity. Without sufficient O 2 to support ATP demands, neuronal activity …

RNA modifications in cancer

Q Tang, L Li, Y Wang, P Wu, X Hou, J Ouyang… - British journal of …, 2023 - nature.com
Currently, more than 170 modifications have been identified on RNA. Among these RNA
modifications, various methylations account for two-thirds of total cases and exist on almost …

Bacterial response to oxidative stress and RNA oxidation

AF Seixas, AP Quendera, JP Sousa, AFQ Silva… - Frontiers in …, 2022 - frontiersin.org
Bacteria have to cope with oxidative stress caused by distinct Reactive Oxygen Species
(ROS), derived not only from normal aerobic metabolism but also from oxidants present in …

The dynamic N1-methyladenosine methylome in eukaryotic messenger RNA

D Dominissini, S Nachtergaele, S Moshitch-Moshkovitz… - Nature, 2016 - nature.com
Gene expression can be regulated post-transcriptionally through dynamic and reversible
RNA modifications. A recent noteworthy example is N 6-methyladenosine (m6A), which …

N6-methyladenine DNA modification in the human genome

CL Xiao, S Zhu, M He, D Chen, Q Zhang, Y Chen, G Yu… - Molecular cell, 2018 - cell.com
Summary DNA N 6-methyladenine (6mA) modification is the most prevalent DNA
modification in prokaryotes, but whether it exists in human cells and whether it plays a role in …

Antibacterial activity of silver nanoparticles of different particle size against Vibrio Natriegens

Y Dong, H Zhu, Y Shen, W Zhang, L Zhang - PloS one, 2019 - journals.plos.org
In this study, we describe the synthesis and characterization of silver nanoparticles (Ag-NPs)
of different sizes and evaluated their antibacterial activity. Particles size and morphology …

Transcriptome-wide mapping reveals reversible and dynamic N1-methyladenosine methylome

X Li, X Xiong, K Wang, L Wang, X Shu, S Ma… - Nature chemical …, 2016 - nature.com
Abstract N 1-Methyladenosine (m1A) is a prevalent post-transcriptional RNA modification,
yet little is known about its abundance, topology and dynamics in mRNA. Here, we show that …

Transfer RNA demethylase ALKBH3 promotes cancer progression via induction of tRNA-derived small RNAs

Z Chen, M Qi, B Shen, G Luo, Y Wu, J Li… - Nucleic acids …, 2019 - academic.oup.com
Transfer RNA is heavily modified and plays a central role in protein synthesis and cellular
functions. Here we demonstrate that ALKBH3 is a 1-methyladenosine (m1A) and 3 …