Delivering optimal renal replacement therapy to critically ill patients with acute kidney injury

R Wald, W Beaubien-Souligny, R Chanchlani… - Intensive care …, 2022 - Springer
Critical illness is often complicated by acute kidney injury (AKI). In patients with severe AKI,
renal replacement therapy (RRT) is deployed to address metabolic dysfunction and volume …

Anticoagulation options for continuous renal replacement therapy in critically ill patients: a systematic review and network meta-analysis of randomized controlled trials

Z Zhou, C Liu, Y Yang, F Wang, L Zhang, P Fu - Critical Care, 2023 - Springer
Background Continuous renal replacement therapy (CRRT) is a widely used standard
therapy for critically ill patients with acute kidney injury (AKI). Despite its effectiveness …

Monitoring of unfractionated heparin in severe COVID-19: an observational study of patients on CRRT and ECMO

AS Streng, TSR Delnoij, MMG Mulder, JWEM Sels… - TH Open, 2020 - thieme-connect.com
Objective Severe cases of coronavirus disease 2019 (COVID-19) can require continuous
renal replacement therapy (CRRT) and/or extracorporeal membrane oxygenation (ECMO) …

How to prolong filter life during continuous renal replacement therapy?

Y Tsujimoto, T Fujii - Critical Care, 2022 - Springer
This article is one of ten reviews selected from the Annual Update in Intensive Care and
Emergency Medicine 2022. Other selected articles can be found online at https://www …

Regional citrate anticoagulation in continuous renal replacement therapy: is metabolic fear the enemy of logic? A systematic review and meta-analysis of randomised …

R Jacobs, W Verbrugghe, K Dams, E Roelant… - Life, 2023 - mdpi.com
Background: Anticoagulation is recommended to maintain the patency of the circuit in
continuous renal replacement therapy (CRRT). However, anticoagulation-associated …

Unfractionated heparin versus nafamostat mesylate for anticoagulation during continuous kidney replacement therapy: an observational study

S Kameda, T Fujii, J Ikeda, A Kageyama, T Takagi… - BMC nephrology, 2023 - Springer
Background Unfractionated heparin sodium and nafamostat mesylate have long been used
as anticoagulants in continuous kidney replacement therapy (CKRT) where citrate is …

Hemorrhage and venous thromboembolism in critically ill patients with COVID-19

C Qiu, T Li, G Wei, J Xu, W Yu, Z Wu, D Li… - SAGE Open …, 2021 - journals.sagepub.com
Objective: The majority of patients with COVID-19 showed mild symptoms. However,
approximately 5% of them were critically ill and require intensive care unit admission for …

Solute Clearance Evaluation and Filter Clotting Prediction in Continuous Renal Replacement Therapy

K Yoshimoto, R Matsuura, Y Komaru… - Journal of Clinical …, 2023 - mdpi.com
Unexpected filter clotting is a major problem in continuous renal replacement therapy
(CRRT). Reduced solute clearance is observed prior to filter clotting. This single-center …

Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement therapy

Y Tsujimoto, S Miki, H Shimada… - Cochrane Database …, 2021 - cochranelibrary.com
Background Acute kidney injury (AKI) is a common complication amongst people who are
critically ill, and it is associated with an increased risk of death. For people with severe AKI …

Citrate and low-dose heparin combined anticoagulation in pediatric continuous renal replacement therapy

D Zhu, J He, Z Xiao, X Zhou, X Zhang - Scientific Reports, 2024 - nature.com
There remains no optimal anticoagulation protocol for continuous renal replacement therapy
(CRRT) with regional citrate anticoagulation (RCA) in pediatric patients with elevated D …