Individual cell heterogeneity within a population can be critical to its peculiar function and
fate. Subpopulations studies with mixed mutants and wild types may not be as informative …

Although a fundamental understanding of the pathogenicity of most biothreat agents has
been elucidated and available treatments have increased substantially over the past …

Micro total analysis (μTAS), also called “lab-on-a-chip (LOC)” technology, promises
solutions for high throughput and highly specific analysis for chemistry, biology and …

The field of micro total analysis systems (μTAS), or “lab on a chip”, has continued to gain
maturity. The importance of μTAS is reflected in both the growing number and the improved …

Biological agents including viruses, bacteria, and other naturally occurring pathogenic
organisms, along with the toxins they produce, are considered far harder to detect and …

Microfluidics is a platform technology that has been used for genomics, proteomics,
chemical synthesis, environment monitoring, cellular studies, and other applications. The …

Systems biology advocates the understanding of biology at the systems-level, which
requires massive information of correlations among individual components in complex …

In this work, we introduce a new two-dimensional chip-based high-performance liquid
chromatography (2D chip-HPLC) approach, which enables multiple transfers from the first …

We generated an aqueous two-phase laminar flow in a microfluidic chip and used the
system to isolate leukocyte and erythrocyte cells from whole blood cells. The microfluidic …

Microfabricated devices will have a large impact on many aspects of analytical chemistry
from clinical diagnostics to security applications due to their small size, ease of fabrication …