Viruses are abundant and diverse entities that have important roles in public health,
ecology, and agriculture. The identification and surveillance of viruses rely on an …

The beginning of the second century of research in the field of virology (the first virus was
discovered in 1898) was marked by its amalgamation with bioinformatics, resulting in the …

We have developed a specialized database, HBVdb (http://hbvdb. ibcp. fr), allowing the
researchers to investigate the genetic variability of Hepatitis B Virus (HBV) and viral …

Hepatitis B virus (HBV) is a diverse, partially double-stranded DNA virus, with 9 genotypes
(A–I), and a putative 10th genotype (J), characterized thus far. Given the broadening interest …

ABSTRACT A natural subviral agent of human hepatitis B virus (HBV), hepatitis delta virus
(HDV), requires only the envelope proteins from HBV in order to maintain persistent …

Abstract jpHMM is a very accurate and widely used tool for recombination detection in
genomic sequences of HIV-1. Here, we present an extension of jpHMM to analyze …

Covalently closed circular DNA (cccDNA) forms the basis for replication and persistence of
hepatitis B virus (HBV) in the chronically infected liver. We have previously shown that viral …

Lately, advances in high-throughput technologies in biomedical research have led to a
dramatic increase in the accessibility of molecular insights at multiple biological levels in …

AIM To detect hyper-conserved regions in the hepatitis B virus (HBV) X gene (HBX) 5'region
that could be candidates for gene therapy. METHODS The study included 27 chronic …

Hepatitis B virus (HBV) is a promising target for therapies based on RNA interference (RNA
i) since it replicates via RNA transcripts that are vulnerable to RNA i silencing. Clinical …