Understanding cancer drug resistance with Sleeping Beauty functional genomic screens: Application to MAPK inhibition in cutaneous melanoma

EY Zhu, JL Schillo, SD Murray, JD Riordan, AJ Dupuy - Iscience, 2023 - cell.com
Combined BRAF and MEK inhibition is an effective treatment for BRAF-mutant cutaneous
melanoma. However, most patients progress on this treatment due to drug resistance. Here …

[HTML][HTML] The local integration preference of the Tf1 retrotransposon in Schizosaccharomyces pombe

Y Cui, Y Guo - Virology, 2022 - Elsevier
Transposons are mobile DNAs that can move to different locations in host genomes. The
integration site selection of transposons is critical for both themselves and host cells. Studies …