Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity

H Cao, L Duan, Y Zhang, J Cao, K Zhang - Signal transduction and …, 2021 - nature.com
Hydrogel is a type of versatile platform with various biomedical applications after rational
structure and functional design that leverages on material engineering to modulate its …

Structurally dynamic hydrogels for biomedical applications: pursuing a fine balance between macroscopic stability and microscopic dynamics

K Zhang, Q Feng, Z Fang, L Gu, L Bian - Chemical Reviews, 2021 - ACS Publications
Owing to their unique chemical and physical properties, hydrogels are attracting increasing
attention in both basic and translational biomedical studies. Although the classical hydrogels …

Collagen hydrogel viscoelasticity regulates MSC chondrogenesis in a ROCK-dependent manner

D Huang, Y Li, Z Ma, H Lin, X Zhu, Y Xiao, X Zhang - Science advances, 2023 - science.org
Mesenchymal stem cell (MSC) chondrogenesis in three-dimensional (3D) culture involves
dynamic changes in cytoskeleton architecture during mesenchymal condensation before …

Collagen-and hyaluronic acid-based hydrogels and their biomedical applications

Q Xu, JE Torres, M Hakim, PM Babiak, P Pal… - Materials Science and …, 2021 - Elsevier
Hydrogels have been widely investigated in biomedical fields due to their similar physical
and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid …

Degradable biomedical elastomers: paving the future of tissue repair and regenerative medicine

B Jia, H Huang, Z Dong, X Ren, Y Lu… - Chemical Society …, 2024 - pubs.rsc.org
Degradable biomedical elastomers (DBE), characterized by controlled biodegradability,
excellent biocompatibility, tailored elasticity, and favorable network design and …

Review of a new bone tumor therapy strategy based on bifunctional biomaterials

J Liao, R Han, Y Wu, Z Qian - Bone research, 2021 - nature.com
Bone tumors, especially those in osteosarcoma, usually occur in adolescents. The standard
clinical treatment includes chemotherapy, surgical therapy, and radiation therapy …

What affects the biocompatibility of polymers?

M Jurak, AE Wiącek, A Ładniak, K Przykaza… - Advances in Colloid and …, 2021 - Elsevier
In recent decades synthetic polymers have gained increasing popularity, and nowadays
they are an integral part of people's daily lives. In addition, owing to their competitive …

Viscoelastic cell microenvironment: hydrogel‐based strategy for recapitulating dynamic ECM mechanics

Y Ma, T Han, Q Yang, J Wang, B Feng… - Advanced Functional …, 2021 - Wiley Online Library
The native extracellular matrix (ECM) generally exhibits dynamic mechanical properties and
displays time‐dependent responses to deformation or mechanical loading, in terms of …

Designing hydrogels for 3D cell culture using dynamic covalent crosslinking

M Rizwan, AEG Baker… - Advanced Healthcare …, 2021 - Wiley Online Library
Designing simple biomaterials to replicate the biochemical and mechanical properties of
tissues is an ongoing challenge in tissue engineering. For several decades, new …

Nanocomposite hydrogels for biomedical applications

S Huang, X Hong, M Zhao, N Liu, H Liu… - Bioengineering & …, 2022 - Wiley Online Library
Nanomaterials' unique structures at the nanometer level determine their incredible functions,
and based on this, they can be widely used in the field of nanomedicine. However …