We present a general framework for incorporating partial differential equation (PDE)-based
models into gradient-based optimization of multidisciplinary systems by integrating FEniCSx …

Mechanical metastructures have been prevailing recently owing to their unusual mechanical
responses. Despite notable progress in designing periodic metastructures, creating irregular …

Projection-based reduced order models rely on offline–online model decomposition, where
the data-based energetic spatial basis is used in the expensive offline stage to obtain …

Imposing nonperiodic boundary conditions for unit cell analyses may be necessary for a
number of reasons in applications, for example, for validation purposes and specific …

Traditionally, the pharmaceutical industry relied on resource-intensive and empirical
methods for process development, optimization, and control. Heuristic approaches to …

Biomolecular condensates help organize the cell cytoplasm and nucleoplasm into spatial
compartments with different chemical compositions. A key feature of such compositional …

Elastomeric solid materials typically exhibit a pronounced viscoelastic response. In this
paper we consider a large deformation viscoelasticity theory for isotropic elastomeric …

Due to the multiple physics involved and their mutual and complex interactions, nuclear
engineers and researchers are constantly working on developing highly accurate Multi …

Biological cells rely on precise spatiotemporal coordination of biochemical reactions to
control their functions. Such cell signaling networks have been a common focus for …

We present an approach to the coupling of mixed-dimensional continua by employing the
mathematically enriched linear Cosserat micropolar model. The kinematical reduction of the …