Recent progress on gene-deleted live-attenuated African swine fever virus vaccines
HLX Vu, DS McVey - npj Vaccines, 2024 - nature.com
Abstract African Swine Fever (ASF) is a highly lethal viral disease in swine, with mortality
rates approaching 100%. The disease has spread to many swine-producing countries …
rates approaching 100%. The disease has spread to many swine-producing countries …
Attenuated African swine fever viruses and the live vaccine candidates: a comprehensive review
J Fan, H Yu, F Miao, J Ke, R Hu - Microbiology Spectrum, 2024 - journals.asm.org
The African swine fever virus (ASFV) is spreading worldwide and causing huge economic
losses to the global pig industry. The ASFV genome is 170–193 kb in length, contains …
losses to the global pig industry. The ASFV genome is 170–193 kb in length, contains …
Deletion of the CD2v gene from the genome of ASFV-Kenya-IX-1033 partially reduces virulence and induces protection in pigs
Infection of pigs with the African swine fever virus (ASFV) leads to a devastating
hemorrhagic disease with a high mortality of up to 100%. In this study, a CD2v gene deletion …
hemorrhagic disease with a high mortality of up to 100%. In this study, a CD2v gene deletion …
The non-classical major histocompatibility complex II protein SLA-DM is crucial for African swine fever virus replication
K Pannhorst, J Carlson, JE Hölper, F Grey, JK Baillie… - Scientific Reports, 2023 - nature.com
African swine fever virus (ASFV) is a lethal animal pathogen that enters its host cells through
endocytosis. So far, host factors specifically required for ASFV replication have been barely …
endocytosis. So far, host factors specifically required for ASFV replication have been barely …
A porcine kidney-derived clonal cell line with clear genetic annotation is highly susceptible to African swine fever virus
H Cao, M Zhang, Z Liao, D Li, X He, H Ma, P Li, X Yu… - Veterinary …, 2024 - Springer
Abstract African Swine Fever virus (ASFV), the causative agent of African swine fever, is a
highly lethal hemorrhagic virus affecting domestic pigs and wild boars. The primary target …
highly lethal hemorrhagic virus affecting domestic pigs and wild boars. The primary target …
Co-deletion of A238L and EP402R genes from a genotype IX African swine fever virus results in partial attenuation and protection in swine
African swine fever virus (ASFV) is the causative agent of African swine fever (ASF),
resulting in up to 100% mortality in pigs. Although endemic in most sub-Saharan African …
resulting in up to 100% mortality in pigs. Although endemic in most sub-Saharan African …
Deletion of the CD2 gene in the virulent ASFV Congo strain affects viremia in domestic swine, but not the virulence
A Koltsov, S Krutko, N Kholod, M Sukher, S Belov… - Animals, 2023 - mdpi.com
Simple Summary African swine fever (ASF) causes serious economic losses to the global
pig industry. Unfortunately, there is currently no effective and safe vaccine, although its …
pig industry. Unfortunately, there is currently no effective and safe vaccine, although its …
[HTML][HTML] Complete Genome Sequencing and Comparative Phylogenomics of Nine African Swine Fever Virus (ASFV) Isolates of the Virulent East African p72 …
African swine fever virus (ASFV) is endemic to African wild pigs (Phacochoerus and
Potamochoerus), in which viral infection is asymptomatic, and Ornithodoros soft ticks …
Potamochoerus), in which viral infection is asymptomatic, and Ornithodoros soft ticks …
A rosin-functionalized plastic surface inactivates African swine fever virus
JD Hemmink, S Shroff, N Chege… - Frontiers in Veterinary …, 2024 - frontiersin.org
African swine fever virus (ASFV) causes a severe hemorrhagic disease in pigs, leading to up
to 100% case fatality. The virus May persist on solid surfaces for long periods; thus, fomites …
to 100% case fatality. The virus May persist on solid surfaces for long periods; thus, fomites …
Special issue “African swine fever and other swine viral diseases in Africa”
ML Penrith, E Okoth, Livio Heath - Viruses, 2023 - mdpi.com
African swine fever (ASF) has become the swine disease of most global concern since its
second escape from Africa in 2007 resulted in its spread to five continents and the …
second escape from Africa in 2007 resulted in its spread to five continents and the …