Roles of neural stem cells in the repair of peripheral nerve injury

C Wang, C Lu, J Peng, C Hu… - Neural regeneration …, 2017 - journals.lww.com
Currently, researchers are using neural stem cell transplantation to promote regeneration
after peripheral nerve injury, as neural stem cells play an important role in peripheral nerve …

Mesenchymal stem cells as a source of dopaminergic neurons: a potential cell based therapy for Parkinson's disease

K Venkatesh, D Sen - Current Stem Cell Research & Therapy, 2017 - ingentaconnect.com
Cell repair/replacing strategies for neurodegenerative diseases such as Parkinson's disease
depend on well-characterized dopaminergic neuronal candidates that are healthy and show …

Bcl-x is required for proper development of the mouse substantia nigra

JM Savitt, SS Jang, W Mu, VL Dawson… - Journal of …, 2005 - Soc Neuroscience
Recent findings have uncovered a role for the Bcl-x gene in the survival of dopaminergic
neurons. The exact nature of this role has been difficult to examine because of the …

Internalization and toxicity of polystyrene nanoplastics on inmortalized human neural stem cells

MC González-Caballero, M de Alba González… - Chemosphere, 2024 - Elsevier
Global plastic production has increased exponentially in recent decades, and a significant
part of it persists in the environment, where it degrades into microplastics and nanoplastics …

Proteomics analysis of prefrontal cortex of Alzheimer's disease patients revealed dysregulated proteins in the disease and novel proteins associated with amyloid-β …

A Montero-Calle, R Coronel… - Cellular and Molecular …, 2023 - Springer
Background Alzheimer's disease (AD) is a progressive, chronic, and neurodegenerative
disease, and the most common cause of dementia worldwide. Currently, the mechanisms …

Neuronal and glial differentiation of human neural stem cells is regulated by amyloid precursor protein (APP) levels

R Coronel, M Lachgar, A Bernabeu-Zornoza… - Molecular …, 2019 - Springer
Amyloid precursor protein (APP) is implicated in neural development as well as in the
pathology of Alzheimer's disease (AD); however, its biological function still remains unclear …

Molecular effects of polystyrene nanoplastics on human neural stem cells

R Martin-Folgar, MC González-Caballero… - Plos one, 2024 - journals.plos.org
Nanoplastics (NPs) have been found in many ecological environments (aquatic, terrestrial,
air). Currently, there is great concern about the exposition and impact on animal health …

[HTML][HTML] Microglia-secreted factors enhance dopaminergic differentiation of tissue-and iPSC-derived human neural stem cells

SI Schmidt, H Bogetofte, L Ritter, JB Agergaard… - Stem Cell Reports, 2021 - cell.com
Microglia have recently been established as key regulators of brain development. However,
their role in neuronal subtype specification remains largely unknown. Using three different …

[HTML][HTML] Cell replacement therapy for Parkinson's disease

R Wijeyekoon, RA Barker - Biochimica et Biophysica Acta (BBA)-Molecular …, 2009 - Elsevier
Parkinson's disease (PD) is a progressive neurodegenerative disorder in which the
degeneration of dopaminergic neurons projecting from the substantia nigra to the striatum is …

Mitochondria and other organelles in neural development and their potential as therapeutic targets in neurodegenerative diseases

S Zhang, J Zhao, Z Quan, H Li, H Qing - Frontiers in Neuroscience, 2022 - frontiersin.org
The contribution of organelles to neural development has received increasing attention.
Studies have shown that organelles such as mitochondria, endoplasmic reticulum (ER) …