Background A number of membrane-anchored proteins are known to be released from cell
surface via ectodomain shedding. The cleavage and release of membrane proteins has …

Background The seminal vesicles synthesise bioactive factors that support gamete function,
modulate the female reproductive tract to promote implantation, and influence …

The innate immune system is the first line of defense against external threats through the
initiation and regulation of inflammation. Macrophage differentiation into functional …

Objective To explore the molecular mechanisms of fatty liver hemorrhagic syndrome (FLHS)
in laying hens, an experiment was conducted to reveal the differences in histopathological …

Pianp (also known as Leda-1) is a type I transmembrane protein with preferential expression
in the mammalian CNS. Its processing is characterized by proteolytic cleavage by a range of …

It was hypothesized that the catalyst nanoceria can increase inflammation/oxidative stress
from the basal and reduce it from the elevated state. Macrophages clear nanoceria. To test …

Abstract Interleukin-1β (IL-1β) plays a critical role in the development of neuropathic pain
through activation of Schwann cells (SCs) after nerve injury. Here, we applied an RNA …

The junctional adhesion molecule (JAM)-B, a member of the immunoglobulin superfamily, is
involved in stabilization of interendothelial cell-cell contacts, formation of vascular tubes …

Leda-1/Pianp is a type-I transmembrane protein which is sorted to the basolateral
membrane domain of polarized epithelial cells. Here, we investigated trafficking …

Leda-1/Pianp is a type I transmembrane protein expressed by CNS cells, murine melanoma
cell line B16F10 and rat liver sinusoidal endothelial cells. The early steps of …