Recent advances in nanocarriers for clinical platinum (II) anticancer drugs

JJ Zhang, QJ Xu, Y Zhang, Q Zhou, R Lv, Z Chen… - Coordination Chemistry …, 2024 - Elsevier
Platinum (II) drugs have been one of the most commonly used anticancer drugs in clinic.
However, drug resistance and severe toxic effects limit their clinical applications. Developing …

End‐/side‐chain fluorescent polymer conjugates: Stimuli‐responsiveness and biological applications

M Kar, TK Mandal - Journal of Polymer Science, 2024 - Wiley Online Library
Smart fluorescent polymers are an interesting class of advanced materials that find
widespread applications in diverse areas ranging from materials chemistry to biology. This …

Structural engineering of star block biodegradable polymer unimolecular micelles for drug delivery in cancer cells

U Pranav, M Malhotra, S Pathan… - … Biomaterials Science & …, 2022 - ACS Publications
The present investigation reports the structural engineering of biodegradable star block
polycaprolactone (PCL) to tailor-make aggregated micelles and unimolecular micelles to …

Genetically engineered virus-like particle-armoured and multibranched DNA scaffold-corbelled ultra-sensitive hierarchical hybridization chain reaction for targeting …

Y Chen, Y Song, X Wang, H Tang, C Li - Biosensors and Bioelectronics, 2024 - Elsevier
Although nucleic acids-based fluorescent biosensors, exemplified by the hybridization chain
reaction (HCR), have exhibited promise as an imaging tool for detecting disease-related …

Ion-/Thermo-Responsive fluorescent perylene-poly (ionic liquid) conjugates: One-pot microwave synthesis, self-aggregation and biological applications

M Kar, M Anas, A Singh, A Basak, P Sen… - European Polymer …, 2022 - Elsevier
This manuscript describes the attachment of alkylvinylimidazolium-based poly (ionic
liquid)(PIL) to the imide positions of perylene bisimide (PBI) to introduce stimuli …

Structural Engineering of Cationic Block Copolymer Architectures for Selective Breaching of Prokaryotic and Eukaryotic Biological Species

R Ghosh, S Pathan, M Jayakannan - ACS Applied Bio Materials, 2024 - ACS Publications
Positively charged antimicrobial polymers are known to cause severe damage to biological
systems, and thus synthetic strategies are urgently required to design next-generation …

Star-Polymer Unimolecular Micelles for Brain Specific Delivery of Anticancer Drug

M Malhotra, M Pardasani, P Srikanth, N Abraham - 2022 - researchsquare.com
Nanocarrier mediated therapeutic delivery to brain tissue remains an impediment by tightly
controlled transportation across the blood brain barrier (BBB). Here, we report a well-defined …