Diabetic sensorimotor peripheral neuropathy (DSPN) is a serious complication of diabetes
mellitus and is associated with increased mortality, lower-limb amputations and distressing …

Doxorubicin (DOX) is widely used as a broad-spectrum anti-tumor anthracycline to treat
various cancers. The serious adverse effects of DOX on cardiotoxicity limit its clinical …

Reactive oxygen species (ROS), such as hydrogen peroxide, are important products of
oxygen metabolism that, when misregulated, can accumulate and cause oxidative stress …

Diabetic neuropathy, with its major clinical sequels, notably neuropathic pain, foot ulcers,
and autonomic dysfunction, is associated with substantial morbidity, increased risk of …

The prevalence of diabetes worldwide is at pandemic levels, with the number of patients
increasing by 5% annually. The most common complication of diabetes is peripheral …

It is estimated that the prevalence rate of Alzheimer's disease (AD) will double by the year
2040. Although currently available treatments help with symptom management, they do not …

Neuropathy is the most common complication of diabetes. As a consequence of
longstanding hyperglycemia, a downstream metabolic cascade leads to peripheral nerve …

Pericytes are a heterogeneous population of cells located in the blood vessel wall. They
were first identified in the 19th century by Rouget, however their biological role and potential …

​ Objective Compared with hemoglobin A1c (HbA1c), continuous glucose monitoring
(CGM) may better capture risk of diabetes complications in patients with chronic kidney …

Pain results from the complex processing of neural signals at different levels of the central
nervous system, with each signal potentially offering multiple opportunities for …