Liver diseases related complications represent a significant source of morbidity and mortality
worldwide, creating a substantial economic burden. Oxidative stress, excessive …

Hepatoprotective effects of natural compounds have been frequently attributed to their
antioxidant properties and the ability to mobilize endogenous antioxidant defense system …

Glycyrrhizin (GL) is a major constituent of licorice root and has been suggested to inhibit the
release of high mobility group box-1 (HMGB1), a protein considered representative of …

High-mobility group box 1 (HMGB1) acts as an early mediator of inflammation and organ
damage in hepatic ischemia-reperfusion (I/R) injury. Glycyrrhizin is a natural anti …

Background High-mobility group box-1 protein (HMGB1) is a nuclear protein that regulates
gene expression throughout the body. It can also become cytoplasmic and function as a …

Aim: Glycyrrhizin (GL) has been found to inhibit extracellular HMGB1 cytokine's activity, and
protect spinal cord, liver and brain against I/R-induced injury in experimental animals. The …

Many recent studies demonstrate that most nanoparticles (NPs) have an adverse or toxic
action on liver. The aim of this study was to investigate the hepatoprotective effect of …

Complementary and alternative medicine soughts and encompasses a wide range of
approaches; its use begun in ancient China at the time of Xia dynasty and in India during the …

Abstract Toll-like receptor 4 (TLR4) recognizes specific structural motifs associated with
microbial pathogens and also responds to certain endogenous host molecules associated …

Background Liver donor shortages stimulate the development of strategies that incorporate
damaged organs into the donor pool. Herein we present a simplified machine perfusion …