Pharmacological postconditioning: a molecular aspect in ischemic injury

H Khan, A Kashyap, A Kaur… - Journal of Pharmacy and …, 2020 - academic.oup.com
Abstract Objective Ischaemia/reperfusion (I/R) injury is defined as the damage to the tissue
which is caused when blood supply returns to tissue after ischaemia. To protect the …

Remote ischemic postconditioning for ischemic stroke: a systematic review and meta-analysis of randomized controlled trials

JJ Zhao, H Xiao, WB Zhao, XP Zhang… - Chinese Medical …, 2018 - mednexus.org
Background: Remote ischemic postconditioning (RIPostC) appears to protect distant organs
from ischemia-reperfusion injury (IRI). However, cerebral protection results have remained …

Exercise-induced cardioprotection is mediated by a bloodborne, transferable factor

MM Michelsen, NB Støttrup, MR Schmidt… - Basic research in …, 2012 - Springer
Exercise protects against myocardial ischemia-reperfusion (IR) injury but the mechanism
remains unclear. Protection can be transferred from a remotely preconditioned human donor …

[PDF][PDF] Apelin-13 protects the heart against ischemia-reperfusion injury through the RISK-GSK-3β-mPTP pathway

S Yang, H Li, L Tang, G Ge, J Ma, Z Qiao… - Archives of Medical …, 2015 - termedia.pl
Results: For the established I/R injury model, apelin-13 and SB216763 (GSK-3β inhibitor)
significantly reduced the infarct size (p< 0.05), which could be abolished by LY294002 (PI3K …

Remote ischemic preconditioning protects against spinal cord ischemia–reperfusion injury in mice by activating NMDAR/AMPK/PGC-1α/SIRT3 signaling

C Gu, F Kong, J Zeng, X Geng, Y Sun, X Chen - Cell & Bioscience, 2023 - Springer
Background To study the protective effects of delayed remote ischemic preconditioning
(RIPC) against spinal cord ischemia–reperfusion injury (SCIRI) in mice and determine …

Effect of Limb Ischemic Preconditioning on Myocardial Injury in Patients Undergoing Mitral Valve Replacement Surgery–A Randomized Controlled Trial–

Q Wu, P Gui, J Wu, D Ding, G Purusram, N Dong… - Circulation …, 2011 - jstage.jst.go.jp
Background: Whether limb ischemic preconditioning (LIPC) is beneficial for patients
undergoing mitral valve replacement (MVR) surgery is unknown. Methods and Results …

HSP 70 and atherosclerosis–protector or activator?

A Bielecka-Dabrowa, M Barylski… - Expert Opinion on …, 2009 - Taylor & Francis
Background: Atherosclerosis and its complications represent the leading cause of morbidity
and mortality. Heat shock protein 70 (HSP70) protects cellular elements from injury by …

Advance in spinal cord ischemia reperfusion injury: Blood–spinal cord barrier and remote ischemic preconditioning

Q Yu, J Huang, J Hu, H Zhu - Life sciences, 2016 - Elsevier
The blood–spinal cord barrier (BSCB) is the physiological and metabolic substance diffusion
barrier between blood circulation and spinal cord tissues. This barrier plays a vital role in …

Heat shock proteins: pathogenic role in atherosclerosis and potential therapeutic implications

A Kilic, K Mandal - Autoimmune diseases, 2012 - Wiley Online Library
Heat shock proteins (HSPs) are a highly conserved group of proteins that are constitutively
expressed and function as molecular chaperones, aiding in protein folding and preventing …

Remote Ischemic conditioning as an emerging tool to improve corticospinal transmission in individuals with chronic spinal cord injury

YK Wu, JM Wecht, OE Bloom, GS Panza… - Current Opinion in …, 2023 - journals.lww.com
RIC is a low-cost intervention easy to deliver in a clinical or home setting. Its potential
application to facilitate neural plasticity and motor learning during rehabilitation training for …