Extracellular vesicles: a rising star for therapeutics and drug delivery

S Du, Y Guan, A Xie, Z Yan, S Gao, W Li, L Rao… - Journal of …, 2023 - Springer
Extracellular vesicles (EVs) are nano-sized, natural, cell-derived vesicles that contain the
same nucleic acids, proteins, and lipids as their source cells. Thus, they can serve as natural …

[HTML][HTML] Modulating the immune system towards a functional chronic wound healing: A biomaterials and Nanomedicine perspective

K Las Heras, I Garcia-Orue, F Rancan, M Igartua… - Advanced Drug Delivery …, 2024 - Elsevier
Chronic non-healing wounds persist as a substantial burden for healthcare systems,
influenced by factors such as aging, diabetes, and obesity. In contrast to the traditionally pro …

Extracellular vesicles: new classification and tumor immunosuppression

M Sheta, EA Taha, Y Lu, T Eguchi - Biology, 2023 - mdpi.com
Simple Summary Extracellular vesicles (EVs) are cell-derived membrane-surrounded
vesicles that carry bioactive molecules and deliver them to recipient cells. Classical EVs are …

Stem cells and angiogenesis: implications and limitations in enhancing chronic diabetic foot ulcer healing

V Rai, R Moellmer, DK Agrawal - Cells, 2022 - mdpi.com
Nonhealing diabetic foot ulcers (DFUs) are a continuing clinical issue despite the improved
treatment with wound debridement, off-loading the ulcer, medication, wound dressings, and …

Research progress of extracellular vesicles and exosomes derived from mesenchymal stem cells in the treatment of oxidative stress-related diseases

W Zhang, T Wang, Y Xue, B Zhan, Z Lai… - Frontiers in …, 2023 - frontiersin.org
There is growing evidence that mesenchymal stem cell-derived extracellular vesicles and
exosomes can significantly improve the curative effect of oxidative stress-related diseases …

Advanced polymer hydrogels that promote diabetic ulcer healing: mechanisms, classifications, and medical applications

Y Xu, Q Hu, Z Wei, Y Ou, Y Cao, H Zhou… - Biomaterials …, 2023 - spj.science.org
Diabetic ulcers (DUs) are one of the most serious complications of diabetes mellitus. The
application of a functional dressing is a crucial step in DU treatment and is associated with …

[HTML][HTML] Regulation of signaling pathways in hair follicle stem cells

X Wang, Y Liu, J He, J Wang, X Chen, R Yang - Burns & trauma, 2022 - academic.oup.com
Hair follicle stem cells (HFSCs) reside in the bulge region of the outer root sheath of the hair
follicle. They are considered slow-cycling cells that are endowed with multilineage …

Exosomes: compositions, biogenesis, and mechanisms in diabetic wound healing

Y Li, Z Zhu, S Li, X Xie, L Qin, Q Zhang, Y Yang… - Journal of …, 2024 - Springer
Diabetic wounds are characterized by incomplete healing and delayed healing, resulting in
a considerable global health care burden. Exosomes are lipid bilayer structures secreted by …

Advances in the applications of Extracellular Vesicle for the treatment of skin photoaging: a Comprehensive Review

CS Cai, GJ He, FW Xu - International Journal of Nanomedicine, 2023 - Taylor & Francis
Skin photoaging is a complex biological process characterized by the accumulation of
oxidative damage and structural changes in the skin, resulting from chronic exposure to …

[HTML][HTML] Status of research on the development and regeneration of hair follicles

D Liu, Q Xu, X Meng, X Liu, J Liu - International Journal of Medical …, 2024 - ncbi.nlm.nih.gov
Hair loss, or alopecia, is a prevalent condition in modern society that imposes substantial
mental and psychological burden on individuals. The types of hair loss, include …