Challenges and advances in serological and molecular tests to aid leprosy diagnosis
L Lopes-Luz, DP Saavedra… - Experimental …, 2023 - journals.sagepub.com
Leprosy is a neglected chronic infectious disease caused by obligate intracellular bacilli,
Mycobacterium leprae and Mycobacterium lepromatosis. Despite multidrug therapy (MDT) …
Mycobacterium leprae and Mycobacterium lepromatosis. Despite multidrug therapy (MDT) …
Accuracy of rapid point-of-care serological tests for leprosy diagnosis: a systematic review and meta-analysis
CP Romero, R Castro, PEA do Brasil… - Memórias do Instituto …, 2022 - SciELO Brasil
BACKGROUND Leprosy is a chronic infectious disease, still endemic in many countries that
may lead to neurological, ophthalmic, and motor sequelae if not treated early. Access to …
may lead to neurological, ophthalmic, and motor sequelae if not treated early. Access to …
Social and environmental conditions related to Mycobacterium leprae infection in children and adolescents from three leprosy endemic regions of Colombia
H Serrano-Coll, HR Mora, JC Beltrán, MS Duthie… - BMC infectious …, 2019 - Springer
Background Leprosy is is still considered a public health issue and in Colombia 7–10% of
new cases are found in children, indicating both active transmission and social inequality …
new cases are found in children, indicating both active transmission and social inequality …
Comparative characteristics of the diagnostic potential of mycobacterial synthetic antigens for the seroriagnosis of lepra and tuberculosis
AG Korolyova-Ushakova, EV Baranova… - Applied biochemistry …, 2019 - Springer
Seven artificial mycobacterial antigens have been synthesized via the conjugation of
synthetic carbohydrate epitopes of M. leprae phenolic glycolipid (PGL-1) and M. tuberculosis …
synthetic carbohydrate epitopes of M. leprae phenolic glycolipid (PGL-1) and M. tuberculosis …
Accuracy of Enzyme‐Linked Immunosorbent Assays (ELISAs) in Detecting Antibodies against Mycobacterium leprae in Leprosy Patients: A Systematic Review and …
OA Espinosa, SM Benevides Ferreira… - Canadian Journal of …, 2018 - Wiley Online Library
IgM against Mycobacterium leprae may be detected by enzyme‐linked immunosorbent
assays (ELISAs) based on phenolic glycolipid I (PGL‐I) or natural disaccharide octyl bovine …
assays (ELISAs) based on phenolic glycolipid I (PGL‐I) or natural disaccharide octyl bovine …
Evaluation of antibody detection against the NDO-BSA, LID-1 and NDO-LID antigens as confirmatory tests to support the diagnosis of leprosy in Yunnan province …
L Jian, S Xiujian, Y Yuangang, X Yan… - Transactions of The …, 2020 - academic.oup.com
Although multidrug therapy (MDT) has been widely used for the treatment of leprosy for
nearly 40 y, the disease remains a public health concern in some areas. The early detection …
nearly 40 y, the disease remains a public health concern in some areas. The early detection …
A new insulin-sensitive enhancer from Silene viscidula, WPTS, treats type 2 diabetes by ameliorating insulin resistance, reducing dyslipidemia, and promoting …
C Zhang, S Qiao, J Wu, W Xu, B Zhao, X Wang - Pharmacological …, 2021 - Elsevier
Wacao pentacyclic triterpenoid saponins (WPTS) is a newly discovered insulin sensitivity
enhancer. It is a powerful hypoglycemic compound derived from Silene viscidula, which has …
enhancer. It is a powerful hypoglycemic compound derived from Silene viscidula, which has …
High seropositivity against NDO-LID in a group of household contacts of leprosy patients. Are we close to leprosy elimination in Colombia?
H Serrano-Coll, M Muñoz, JC Beltrán… - … and Global Health, 2023 - Taylor & Francis
Introduction. Leprosy is a chronic infectious disease caused by two mycobacteria
(Mycobacterium leprae and Mycobacterium lepromatosis). The household contacts (HHC) of …
(Mycobacterium leprae and Mycobacterium lepromatosis). The household contacts (HHC) of …
Detection of Mycobacterium leprae infection in family clusters from six leprosy-endemic regions in Colombia
H Serrano-Coll, Y Osorio-Leal… - Transactions of The …, 2022 - academic.oup.com
Background Leprosy is a chronic infectious disease caused by Mycobacterium leprae, which
continues to be endemic in tropical countries, making it necessary to implement strategies …
continues to be endemic in tropical countries, making it necessary to implement strategies …
Evaluation of antigen-specific immune responses for leprosy diagnosis in a hyperendemic area in China
X Chen, YG You, YH Yuan, LC Yuan… - PLoS neglected …, 2018 - journals.plos.org
Objective To evaluate antigen-specific immune responses for leprosy diagnosis in a
hyperendemic area in China. Methods Eighty-three leprosy patients and 161 non-leprosy …
hyperendemic area in China. Methods Eighty-three leprosy patients and 161 non-leprosy …