[HTML][HTML] Molecular mimicry and autoimmunity

M Rojas, P Restrepo-Jiménez, DM Monsalve… - Journal of …, 2018 - Elsevier
Molecular mimicry is one of the leading mechanisms by which infectious or chemical agents
may induce autoimmunity. It occurs when similarities between foreign and self-peptides …

Genetics and epigenetics of primary Sjögren syndrome: implications for future therapies

GE Thorlacius, A Björk… - Nature Reviews …, 2023 - nature.com
In primary Sjögren syndrome (pSS), chronic inflammation of exocrine glands results in tissue
destruction and sicca symptoms, primarily of the mouth and eyes. Fatigue, arthralgia and …

Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells

B Khatri, KL Tessneer, A Rasmussen… - Nature …, 2022 - nature.com
Sjögren's disease is a complex autoimmune disease with twelve established susceptibility
loci. This genome-wide association study (GWAS) identifies ten novel genome-wide …

A summary on the genetics of systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, and Sjögren's syndrome

L Ortíz-Fernández, J Martín… - Clinical Reviews in …, 2023 - Springer
Systemic lupus erythematosus, systemic sclerosis, rheumatoid arthritis, and Sjögren's
syndrome are four major autoimmune rheumatic diseases characterized by the presence of …

An Overview of the Dry Eye Disease in Sjögren's Syndrome Using Our Current Molecular Understanding

KY Wu, M Kulbay, C Tanasescu, B Jiao… - International Journal of …, 2023 - mdpi.com
Sjögren's syndrome is a chronic and insidious auto-immune disease characterized by
lymphocyte infiltration of exocrine glands. The patients typically present with ocular surface …

Genetics and epigenetics in primary Sjögren's syndrome

J Imgenberg-Kreuz, A Rasmussen, K Sivils… - …, 2021 - academic.oup.com
Primary Sjögren's syndrome (pSS) is considered to be a multifactorial disease, where
underlying genetic predisposition, epigenetic mechanisms and environmental factors …

Advances in pathogenesis of Sjögren's syndrome

Y Tian, H Yang, N Liu, Y Li… - Journal of immunology …, 2021 - Wiley Online Library
Sjögren's syndrome (SS) is a chronic autoimmune disease of unknown etiology that mainly
involves exocrine glands. Patients present with dry mouth and eyes, fever, arthralgia, and …

Outline of Salivary Gland Pathogenesis of Sjögren's Syndrome and Current Therapeutic Approaches

Y Yura, M Hamada - International Journal of Molecular Sciences, 2023 - mdpi.com
Sjögren's syndrome (SS) is an autoimmune disease characterized by the involvement of
exocrine glands such as the salivary and lacrimal glands. The minor salivary glands, from …

The role of interferons in the pathogenesis of Sjögren's syndrome and future therapeutic perspectives

N Del Papa, A Minniti, M Lorini, V Carbonelli… - Biomolecules, 2021 - mdpi.com
There is a great deal of evidence pointing to interferons (IFNs) as being key cytokines in the
pathogenesis of different systemic autoimmune diseases, including primary Sjögren's …

Transcriptomic and single-cell analysis reveals regulatory networks and cellular heterogeneity in mouse primary sjögren's syndrome salivary glands

E Horeth, A Oyelakin, EAC Song, M Che… - Frontiers in …, 2021 - frontiersin.org
Sjögren's Syndrome (SS) is a chronic autoimmune disease of unknown etiology which
primarily affects the salivary and lacrimal glands resulting in the loss of secretory function …