Background and Purpose: The diverse causes of right-sided heart failure (RHF) include,
among others, primary cardiomyopathies with right ventricular (RV) involvement, RV …

Congenital heart disease is the most frequently occurring congenital disorder affecting≈
0.8% of live births. Thanks to great efforts and technical improvements, including the …

2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease: A
Report of the American College of Cardiology/American Heart Association Task Force on …

The recommendations listed in this guideline are, whenever possible, evidence-based. An
initial extensive evidence review, which included literature derived from research involving …

The past 60 years have brought remarkable advancements in the diagnosis and treatment of
congenital heart disease (CHD). Early diagnosis and improvements in cardiac surgery and …

Abstract Tetralogy of Fallot (ToF) is the most common type of cyanotic congenital heart
disease. Since the first surgical repair in 1954, treatment has continuously improved. The …

Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart defect. We explore
“hot topics” to highlight areas of emerging science for clinicians and scientists in moving …

The myocardial interstitial or extracellular space exists as a complex and dynamic
environment, vital for normal cardiac structure and function. The physiological pathways for …

Emerging heart failure (HF) concepts in the growing population of adults with congenital
heart disease (ACHD) are reviewed in the following article with a focus on individuals with …

Right ventricular dysfunction is a major determinant of outcome in patients with complex
congenital heart disease, as in tetralogy of Fallot. In these patients, right ventricular …