Inferring tumour evolution from single-cell and multi-sample data

E Ross - 2018 - repository.cam.ac.uk
Tumour development has long been recognised as an evolutionary process during which
cells accumulate mutations and evolve into a mix of genetically distinct cell subpopulations …

Statistical methods for deciphering intra-tumor hereterogeneity: challenges and opportunities for cancer clinical management

J Abecassis - 2020 - pastel.hal.science
Accessing the repertoire of cancer somatic alterations has been instrumental in our current
understanding of carcinogenesis. However, efforts in genomic characterization of cancers …