There is significant interest in understanding the cellular mechanisms responsible for
expedited healing response in various oral tissues and how they are impacted by systemic …

Periodontitis is a widespread inflammatory disease that leads to loss of the tooth supporting
periodontal tissues. The few therapies available to regenerate periodontal tissues have high …

Periodontium supports teeth in a mechanically stimulated tissue environment, where
heterogenous stem/progenitor populations contribute to periodontal homeostasis. In this …

The tissue-resident skeletal stem cells (SSCs), which are self-renewal and multipotent,
continuously provide cells (including chondrocytes, bone cells, marrow adipocytes, and …

Stem cells play a critical role in bone regeneration. Multiple populations of skeletal stem
cells have been identified in long bone, while their identity and functions in alveolar bone …

Periodontal tissue stem cells, which play a crucial role in maintaining the homeostasis of
periodontal tissues, are found in the periodontal ligament (PDL). These cells have long been …

Osseointegration is the key issue for implant success. The in vivo properties of cell
populations driving the osseointegration process have remained largely unknown. In the …

The periodontal ligament (PDL) contains mesenchymal stem cells (MSCs) that can
differentiate into osteoblasts, cementoblasts, and fibroblasts. Nevertheless, the distribution …

Wnt–β-catenin signaling plays a key role in orthodontic tooth movement (OTM), a common
clinical practice for malocclusion correction. However, its targeted periodontal ligament …

Physiologically, teeth and periodontal tissues are exposed to occlusal forces throughout
their lifetime. Following occlusal unloading, unbalanced bone remodeling manifests as a net …