Curcumin (1, 7-bis-(4-hydroxy-3-methoxyphenyl)-hepta-1, 6-diene-3, 5-dione) is a natural
lipophilic polyphenol that exhibits significant pharmacological effects in vitro and in vivo …

Nowadays, one of the leading causes of death in humans is cancer, which is still on the rise
globally and is in great need of intense study on the pathogenic mechanism and effective …

Colorectal cancer (CRC) is one of most common malignancies worldwide and its incidence
is still growing. In spite of recent advances in targeted therapies, their clinical efficacy has …

Curcumin diffuses through cell membranes into the endoplasmic reticulum, mitochondria,
and nucleus, where it exerts actions, as an antioxidant property. Therefore, its use has been …

Free radicals, generally composed of reactive oxygen species (ROS) and reactive nitrogen
species (RNS), are generated in the body by various endogenous and exogenous systems …

Ischemic disease is a class of diseases in which an organ is ischemic due to vascular
occlusion, a major contributor to death and disability worldwide. However, when the blood …

Intact epithelial barrier and mucosal immune system are crucial for maintaining intestinal
homeostasis. Previous study indicated that Dendrobium officinale polysaccharides (DOPS) …

Despite the progress that has occurred in recent years in the development of therapies to
treat painful and inflammatory diseases, there is still a need for effective and potent …

Chronic diseases account for over 60% of all deaths worldwide according to the World
Health Organization reports. Majority of cases are triggered by environmental exposures that …

Colorectal cancer (CRC) is associated with significant morbidity and mortality in the US and
worldwide. CRC is the second most common cancer‐related death in both men and women …