Synthesis, bioactivity, and molecular docking of pyrazole bearing Schiff-bases as prospective dual alpha-amylase and alpha-glucosidase inhibitors with antioxidant …
LM Aroua, IS Alkhaibari, FM Alminderej… - Journal of Molecular …, 2025 - Elsevier
A series of pyrazole-Schiff base derivatives, 3a-i, were synthesized by reacting arylamines
2a-i with pyrazole aldehyde 1, utilizing two catalysts: ammonium chloride (catalyst A) or …
2a-i with pyrazole aldehyde 1, utilizing two catalysts: ammonium chloride (catalyst A) or …
[HTML][HTML] Copper (ii) complexes derived from naphthalene-based halogenated Schiff bases: synthesis, structural analysis, DFT computational studies and in vitro …
SD Oladipo, RC Luckay - New Journal of Chemistry, 2024 - pubs.rsc.org
Two halogenated Schiff bases namely,(E)-1-(((2, 6-dichlorophenyl) imino) methyl)
naphthalen-2-ol (L1) and (E)-1-(((4-bromo-2, 6-dichlorophenyl) imino) methyl) naphthalen-2 …
naphthalen-2-ol (L1) and (E)-1-(((4-bromo-2, 6-dichlorophenyl) imino) methyl) naphthalen-2 …
[HTML][HTML] Evaluating the antidiabetes and antioxidant activities of halogenated Schiff bases derived from 4-(diethylamino) salicylaldehyde: in vitro antidiabetes …
SD Oladipo, RC Luckay, KA Olofinsan - Scientific Reports, 2024 - nature.com
Six Schiff bases with general name 5-(diethylamino)-2-(((halophenyl) imino) methyl) phenol
(where halo= 4-fluoro (H1), 2-fluoro (H2), 2-bromo (H3), 4-bromo (H4), 4-chloro (H5) and 3 …
(where halo= 4-fluoro (H1), 2-fluoro (H2), 2-bromo (H3), 4-bromo (H4), 4-chloro (H5) and 3 …
Sulfaquinoxaline-derived Schiff bases: Synthesis, characterization, biological profiling, and computational modeling
Here, six sulfaquinoxaline Schiff bases were synthesized, and various analytical techniques
such as FTIR, 1 HNMR, and 13 CNMR were employed for the characterization. Additionally …
such as FTIR, 1 HNMR, and 13 CNMR were employed for the characterization. Additionally …
[HTML][HTML] Structural studies, DFT computational analysis and inhibitory potential of (E)-N'-(2-bromophenyl)-N-(2, 6-diisopropylphenyl) formamidine against CDK1 and …
SD Oladipo, RC Luckay, AA Badeji, SZ Zamisa… - Journal of Molecular …, 2025 - Elsevier
Abstract Compound (E)-N'-(2-bromophenyl)-N-(2, 6-diisopropylphenyl) formamidine (BDF)
was synthesized and elucidated by FT-IR, UV–Visible, 13 C & 1 H-NMR, spectroscopy as …
was synthesized and elucidated by FT-IR, UV–Visible, 13 C & 1 H-NMR, spectroscopy as …
A homochiral Nickel (II) Complex [Ni (P'N) 2] Cl2: Synthesis, Characterization, Crystal Structure, Luminescence, DFT and Hirshfeld Surface Studies
A new complex ([Ni (P'N) 2] Cl 2) is synthesized from an anhydrous NiCl 2 and a bidentate
P'N (S, S)-NH 2 CHPhCHPhPPh 2) ligand with an enantiopure ethylene backbone. The …
P'N (S, S)-NH 2 CHPhCHPhPPh 2) ligand with an enantiopure ethylene backbone. The …
Oleanolic acid purified from the stem bark of Olax subscorpioidea Oliv. inhibits the function and catalysis of human 17β-hydroxysteroid dehydrogenase 1
Cancer is a leading cause of global death. Medicinal plants have gained increasing
attention in cancer drug discovery. In this study, the stem bark extract of Olax …
attention in cancer drug discovery. In this study, the stem bark extract of Olax …
[HTML][HTML] Additively Manufactured Continuous Processing Reactor System for Producing Liquid-Based Pharmaceutical Substances
A Khabiyev, S Dilibal, A Mussulmanbekova… - Applied Sciences, 2024 - mdpi.com
In this study, an AM-based continuous processing reactor system was designed,
manufactured, and assembled on a laboratory scale for the generation of pharmaceutical …
manufactured, and assembled on a laboratory scale for the generation of pharmaceutical …
[HTML][HTML] Cannabis sativa L. essential oil: Chemical composition, anti-oxidant, anti-microbial properties, and acute toxicity: In vitro, in vivo, and in silico study
This study evaluated the volatile components of Cannabis sativa L. essential oils (CSEOs)
and their pharmacological potential in vitro, in animal, and in silico. The anti-oxidant …
and their pharmacological potential in vitro, in animal, and in silico. The anti-oxidant …
Exploring the therapeutic potential of prolinamides as multi-targeted agents for Alzheimer's disease treatment: molecular docking and molecular dynamic simulation …
Alzheimer's disease (AD) presents a significant global health challenge, with its prevalence
expected to rise sharply in the coming years. Despite extensive research, effective …
expected to rise sharply in the coming years. Despite extensive research, effective …